| Type | Description |
|---|---|
| Definition | Liprin-alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:52:00 | Our live data support a "serial synapse formation" model, where at any time point only 1-2 "synaptogenic" filopodia suppress the synaptic competence of other filopodia through competition for synaptic seeding factors. Loss of the synaptic seeding factors Syd-1 and Liprin-alpha leads to a loss of this suppression, filopodial destabilization, and reduced synapse formation. | 31353313 |
| 2014-08-16 11:27:00 | Loss of function of liprin-alpha causes accumulation of ectopic materials in synapses of distal axons. | 24948803 |
| 2011-01-01 11:24:00 | Context-specific interactions among three liprins (liprin-alpha, -beta, and -gamma) suggest that the R7 photoreceptor and neuromuscular junction synapses differ in their assembly mechanisms. | 21084592 |
| 2010-01-21 12:36:00 | Data demonstrate that N-cadherin, DLAR, and Liprin-alpha function in a complex to regulate adhesive interactions between pre- and post-synaptic cells and provide a novel mechanism for controlling the activity of Liprin-alpha in the developing growth cone. | 19766621 |
| 2010-01-21 00:00:00 | Results suggest that Liprin-alpha does not simply act by regulating receptor tyrosine phosphatase LAR localization but also has LAR-independent functions. | 16864797 |
| Type | IDs |
|---|---|
| Synonymous | CG11199, DLiprin, DLiprin-alpha, Dliprin-alpha, Dmel\CG11199, LIP, LIP.1, LIP1, Liprin, lip-alpha, lpr, oos |
| Gene |
UniProtKB-ID:
Q9VM93_DROME,
M9PC73_DROME,
M9PCR7_DROME,
M9PCD4_DROME
UniprotKB:
Q9VM93,
M9PC73,
M9PCR7,
M9PCD4
UniParc:
UPI0002941B6C,
UPI00001245D6,
UPI00029473CB,
UPI000000C366
EMBL:
BT004484,
AE014134
EnsemblGenome:
FBgn0046704
KO:
dme:Dmel_CG11199
|
| Nucleutide sequences |
EMBL-CDS:
AAN10596.1,
AAF52430.2,
AAO42648.1,
AGB92689.1,
AGB92690.1,
AGB92691.1
Gene_ORFName:
CG11199,
Dmel_CG11199,
Dmel_CG11199,
CG11199,
CG11199,
Dmel_CG11199,
Dmel_CG11199,
CG11199
EnsemblGenome_TRS:
FBtr0079300,
FBtr0079301,
FBtr0329941,
FBtr0329942,
FBtr0329943
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0078931,
FBpp0078930,
FBpp0302973,
FBpp0302974,
FBpp0302975
RefSeq:
NP_723208.1,
NP_001260155.1,
NP_001260154.1,
NP_609067.2,
NP_001260153.1
|
| Others |
UniRef100:
UniRef100_M9PC73,
UniRef100_M9PCR7,
UniRef100_M9PCD4
UniRef90:
UniRef90_M9PCD4
UniRef50:
UniRef50_M9PCD4
UniGene:
Dm.12197
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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