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24888 Bcl2l1

24888

Bcl2l1

Bcl2-like 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition Bcl2-like 1

研究结论

Date Results Publications
2018-06-02 11:19:00 evidence that impaired expression of CK2 results in destabilization of the Bcl-2 mammalian homolog Bcl-xL, which is known to stabilize the mitochondrial membrane potential, through a mechanism involving disruption of the chaperone function of heat shock protein 90. 28597245
2018-02-17 10:09:00 our results showed that the expression of platelet-derived miR-142-3p and the apoptosis were both significantly increased in ECs during hypertension. The present results suggested that platelet-derived miR-142-3p is delivered into ECs via PMPs, and may modulate the expression of target molecule- BCL2L1, which may subsequently display a negative function by modulating EC apoptosis in hypertension. 28478796
2017-04-01 12:12:00 PGAM5 controls cardiomyocyte apoptosis induced by MIRI through regulating Keap1-mediated Bcl-xL degradation, which may supply a novel molecular target for acute myocardial infarction (AMI) therapy. 27815660
2017-03-25 11:50:00 the expression of the genes that encode main pro- and antiapoptotic BAX and BCL-XL proteins, as well as caspase 3 (the main effector of apoptosis), in different brain structures of rats that were selected on a high aggression towards human (or its absence) was studied. 27830683
2017-03-25 11:42:00 The activation of Bcl-xL expression in the hippocampus by lithium, demonstrated for the first time in this study, suggests an important role of this protein in the therapeutic effects of lithium in the treatment of stress-induced psychoemotional disorders. 28320276

名称对应

Type IDs
Synonymous Bcl-xl, Bcl2l, Bclx, bcl-X
Gene
UniProtKB-ID: B2CL1_RAT, Q548R7_RAT, Q7TS62_RAT
UniprotKB: P53563, Q548R7, Q7TS62
UniParc: UPI0000126835, UPI00000008A7, UPI00001AA8FC, UPI000002A4C9
EMBL: AABR07054333, AABR07054332, S76513, AABR07054331, CH474050, U34963, U10579, S78284, BC094213, AABR07054330, AY141038, U72349, X82537, U72350, AF279286
Ensembl: ENSRNOG00000007946
KO: rno:24888
Nucleutide sequences
EMBL-CDS: AAH94213.1, CAA57886.1, AAC60701.2, AAC60702.1, AAA77686.1, CAA57887.1, AAB17352.1, AAB17353.1, AAA19257.1, EDL86042.1, AAF81262.1, EDL86043.1, AAN17784.1
Gene_ORFName: rCG_37256, rCG_37257
Ensembl_TRS: ENSRNOT00000010762, ENSRNOT00000047416, ENSRNOT00000091419
Protein sequencees
Ensembl_PRO: ENSRNOP00000010762, ENSRNOP00000069758, ENSRNOP00000043542
RefSeq: XP_017446968.1, XP_006235326.1, NP_001028843.1, NP_113723.2, NP_001028844.1, XP_017446969.1, XP_017446967.1, NP_001028842.1, XP_006235327.1
Others
UniRef100: UniRef100_Q548R7, UniRef100_Q7TS62, UniRef100_P53563
UniRef90: UniRef90_P53563, UniRef90_P53563-3, UniRef90_Q64373-2
UniRef50: UniRef50_Q64373-2, UniRef50_P53563
UniGene: Rn.10323

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