| Type | Description |
|---|---|
| Definition | von Hippel-Lindau tumor suppressor |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:51:00 | VHL gene methylation contributes to excessive erythrocytosis in chronic mountain sickness rat model by upregulating the HIF-2alpha/EPO pathway. | 33309718 |
| 2018-08-11 11:11:00 | VHL functions to induce neuronal differentiation of neural stem/progenitor cells and skin-derived precursors. | 29401731 |
| 2017-04-22 10:14:00 | that the change of VHL protein expression was related to neuronal apoptosis after spinal cord injury | 27324785 |
| 2015-12-05 10:12:00 | we observed that microtubule network stabilization downregulated Ran-mediated pVHL nuclear accumulation, which in turn led to the upregulation of HIF-1alpha protein | 25779090 |
| 2012-10-20 10:20:00 | The protein levels of HIF-1alpha were down-regulated through overexpression of pVHL and were up-regulated through knockdown of pVHL in hypoxic cardiomyocytes. | 22506063 |
| Type | IDs |
|---|---|
| Synonymous | Vhlh |
| Gene |
UniProtKB-ID:
VHL_RAT
UniprotKB:
Q64259
UniParc:
UPI00000E72D9
EMBL:
U14746,
S81658,
S80345
Ensembl:
ENSRNOG00000010258
KO:
rno:24874
|
| Nucleutide sequences |
EMBL-CDS:
AAA86874.1,
AAB35675.1,
AAP32238.1
Ensembl_TRS:
ENSRNOT00000013727
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000013727
RefSeq:
NP_434688.1
|
| Others |
UniRef100:
UniRef100_Q64259
UniRef90:
UniRef90_P40338
UniRef50:
UniRef50_P40338
UniGene:
Rn.11059
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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