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24816 Tbxa2r

24816

Tbxa2r

thromboxane A2 receptor

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition thromboxane A2 receptor

研究结论

Date Results Publications
2020-10-10 13:00:00 Thromboxane A2 receptors mediate chronic mechanoreflex sensitization in a rat model of simulated peripheral artery disease. 32530751
2018-03-10 10:42:00 We conclude that hyperglycemia activates thromboxane A2 receptor to impair the integrity and function of blood-brain barrier via the ROCK-PTEN-Akt-eNOS pathway. 28415790
2017-08-19 10:20:00 the long-lasting oligemia following cortical spreading depression consists of at least two distinct temporal phases, mediated by preferential actions of COX-1- and COX-2-derived prostanoids: an initial phase mediated by COX-1 that involves TXA2 followed by a later phase, mediated by COX-2 and PGF2alpha. 27178425
2017-02-18 10:49:00 Data suggest that thromboxane A2/Tbxa2r-mediated vasoconstriction of intracavernous small penile arteries depends on Ca2+ influx through L-type calcium channels and TRP (transient receptor potential) channels, and ROCK- (Rho kinase)-dependent mechanisms in vascular smooth muscle. 26708952
2016-05-21 10:52:00 The experiments suggest that in the SHR but not the WKY aorta, alpha1 -adrenoceptor activation desensitizes TP receptors through activation of 25857252

名称对应

Type IDs
Gene
UniProtKB-ID: TA2R_RAT
UniprotKB: P34978
UniParc: UPI0000136858
EMBL: D32080, D21158
Ensembl: ENSRNOG00000020585
KO: rno:24816
Nucleutide sequences
EMBL-CDS: BAA06844.1, BAA04694.1
Ensembl_TRS: ENSRNOT00000027932
Protein sequencees
Ensembl_PRO: ENSRNOP00000027932
RefSeq: NP_058750.2, XP_006240908.1
Others
UniRef100: UniRef100_P34978
UniRef90: UniRef90_P34978
UniRef50: UniRef50_P34978
UniGene: Rn.44614

全选

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研究热度

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