Tap1 - transporter 1, ATP binding cassette subfamily B member-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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24811 Tap1

基因描述

Type	Description
Definition	transporter 1, ATP binding cassette subfamily B member

研究结论

Date	Results	Publications
2017-09-23 11:19:00	Study compared the biochemical properties of the nucleotide-binding domains (NBD) of human and rat TAP1; suggests that although the D-helix sequence is not conserved in ABC transporters, its precise positioning within the NBD structure has a critical role in NBD dimerization.	28542489
2010-01-21 00:00:00	Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B	12470953
2010-01-21 00:00:00	the distinct nucleotide binding behaviour of TAP1 and TAP2 is controlled by the nonhomologous C-terminal tails of the two TAP chains	14622282
2010-01-21 00:00:00	the biogenesis of functional TAP depends on the assembly of preexisting TAP1 with newly synthesized TAP2, but not vice versa	16624807
2010-01-21 00:00:00	The transmembrane core complex of transporter associated with antigen processing (TAP)1 and TAP2 is sufficient for UL49.5 protein of bovine herpesvirus type-1 to mediate its inhibitory activity.	18802093

名称对应

Type	IDs
Synonymous	Abcb2, Cim, Tap2
Gene	UniProtKB-ID: P97561_RAT, P97949_RAT UniprotKB: P97561, P97949 UniParc: UPI00000E89C2, UPI00000E894F EMBL: CH473988, BC101854, AC098547, Y10234, Y10235, BX883043, Y10230 Ensembl: ENSRNOG00000000457 KO: rno:24811
Nucleutide sequences	EMBL-CDS: CAA71284.1, AAI01855.1, CAE83941.1, EDL96810.1, CAA71283.1, CAA71279.1 Gene_ORFName: rCG_61064 Ensembl_TRS: ENSRNOT00000000529
Protein sequencees	Ensembl_PRO: ENSRNOP00000000529 RefSeq: NP_114444.2
Others	UniRef100: UniRef100_P97949, UniRef100_P97561 UniRef90: UniRef90_P36370 UniRef50: UniRef50_P36370 UniGene: Rn.10763

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
28542489	D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain. PLoS ONE Ahmet S Vakkasoglu , Sriram Srikant , Rachelle Gaudet	2017-01-01	-
24586191	Natural polymorphisms in Tap2 influence negative selection and CD4â¶CD8 lineage commitment in the rat. PLoS Genet. Jonatan Tuncel , Sabrina Haag , Anthony C Y Yau , Ulrika Norin , Amelie Baud , Erik LÃ¶nnblom , Klio Maratou , A Jimmy Ytterberg , Diana Ekman , Soley Thordardottir , Martina Johannesson , Alan Gillett , EURATRANS Consortium , Pernilla Stridh , Maja Jagodic , Tomas Olsson , Alberto FernÃ¡ndez-Teruel , Roman A Zubarev , Richard Mott , Timothy J Aitman , Jonathan Flint , Rikard Holmdahl	2014-02-01	-
21843574	Association of TAP 1 and 2 gene polymorphisms with human immunodeficiency virus-tuberculosis co-infection. Hum. Immunol. Sharada Ramaseri Sunder , Surekha Rani Hanumanth , Sumanlatha Gaddam , Subbanna Jonnalagada , Vijaya Lakshmi Valluri	2011-10-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19946888	Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins	2010-01-01	MED6, PDCD6IP, MED16, PIGK, DNAJB6, FARSB, DNM1L, ABCF2, HUWE1, ARPC3, ACTR3, ACTR2, RAD50, PREB, ACTR1B, LRPPRC, TRAP1, BCAP31, PLXNC1, LPCAT3, TNK2, PSME3, MPHOSPH9, FLOT1, DDX39A, AK6, ADAM10, PLIN3, CALCOCO2, CDK9, ABCC4, ZMPSTE24, AKAP8, BET1, MARCH6, KATNB1, ADAR, EMC8, BTN3A3, ATP8A1, NDC80, CDIPT, PGRMC2, TUBGCP3, ECI2, COG5, SLC25A17, LRRC41, SYNCRIP, MYBBP1A, DDX17, CHERP, HYOU1, IPO7, NOP56, ARL6IP5, HTATIP2, AGPAT1, ARFGEF2, RABAC1, SLU7, PRPF8, PAICS, CENPE, PMVK, KHDRBS1, CELF1, GNA13, CFL1, MGEA5, YME1L1, STAG2, CTSC, GIPC1, HBS1L, TUBGCP2, PGRMC1, MAN1A2, PNPLA6, MAGED2, ADCY3, EHD1, TOMM34, ERP29, YWHAQ, ASCC3, GCN1, IMMT, ILVBL, SLC27A4, SLC27A3, KIF2C, GLIPR1, CPSF6, DDX52, WWP2, CNTRL, CHD4, KRR1
19217216	Transporter associated with antigen processing and the chaperone tapasin: are non-classical HLA genes keys to the pathogenesis of schizophrenia? Med. Hypotheses Barbara Fellerhoff , Rudollf Wank	2009-05-01	-
19480848	TAP1 and TAP2 polymorphisms associated with ankylosing spondylitis in genetically homogenous Chinese Han population. Hum. Immunol. Mingliang Feng , Biao Yin , Tong Shen , Qing Ma , Lidong Liu , Jiewei Zheng , Yulin Zhao , Kaicheng Qian , Dazhuang Liu	2009-04-01	-
19492245	Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: association with disease progression. Scand. J. Gastroenterol. Qiao Liu , Chunyan Hao , Peng Su , Juanhong Shi	2009-01-01	Tap1, Tap2, Psmb9
18802093	The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex. J. Immunol. Marieke C Verweij , Danijela Koppers-Lalic , Sandra Loch , Florian Klauschies , Henri de la Salle , Edwin Quinten , Paul J Lehner , Arend Mulder , Michael R Knittler , Robert TampÃ© , Joachim Koch , Maaike E Ressing , Emmanuel J H J Wiertz	2008-10-01	-
18614015	A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha	2008-07-11	Acacb, Hscb, Gadd45gip1, Lars2, Acad11, Chchd10, Nt5dc3, Slc25a41, Nt5m, Cyp27a1, Acly, Ndufb11, Gldc, Rexo2, Rars, Aldh6a1, Slc25a47, Rdh14, Ppif, Ldhal6b, Me2, Glyat, Slc25a45, Acaca, Nt5c3, Mrpl10, Mrpl41, Mrpl30, Aldh1l1, Mthfs, Shmt2, Atic, Mthfd1, Mat2b, Fam210a, Gpt2, Lyrm2, Rdh13, Mtrf1l, Atad3a, Rars2, Sccpdh, Me3, Maob, Dut, Cyp11b1, Fdps, Akr7a5, Msra, Krt5, Cox6b1, Qdpr, Acat1, Acat2, Aldh7a1, Pcca, Etfb, Etfa, Nudt19, Acadl, Acadm, Acadvl, Acaa1a, Acads, Aco1, Aco2, Prosc, Afg3l1, Adsl, Agxt, Ak2, Ak4, Akap1, Alas1, Alas2, Abcd1, Aldh2, Aldh3a2, Gfer, Acsm1, Slc25a4, Slc25a5, Prdx3, Prdx6, Mrps2, Arg2, Rhoa, Atp5a1, Atp5b, Atp5c1, Atp5f1, Atp5g1, Atp5j, Atp5k, Atpif1, Auh, Akr1b7, Bad, Bak1

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