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24806 Tac1

24806

Tac1

tachykinin, precursor 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition tachykinin, precursor 1

研究结论

Date Results Publications
2020-10-10 13:02:00 Overexpression of TIMP3 inhibits discogenic pain by suppressing angiogenesis and the expression of substance P in nucleus pulposus. 31922222
2019-10-26 12:43:00 The tachykinin substance P increases neuronal excitability, participates in homeostatic control, but induces brain oedema after stroke or trauma. Blocking the NK-1 receptor prevents the occurrence of cortical spreading depression waves induced by substance P dissolved in aqua and prevents the ignition of cortical spreading depression waves by aqua alone. 30518958
2019-04-06 11:03:00 findings suggest that both SP and TGFbeta-1 can stimulate tenocyte fibrogenic processes, albeit differently. TGFbeta-1 pathway signaling was involved in CCN2 production at all time points examined, while SP induced collagen type I production independently prior to the onset of signaling through the TGFbeta-1 pathway. 28399671
2018-07-14 11:27:00 BM-EPCs along with SP promote the pericyte-like coverage of BM-MSCs on endothelial tubules possibly through the induction of PDGF-BB. 28791754
2018-06-02 11:59:00 These findings reported here for the first time suggest an important role for a SP/NK1R system, either as genetic and/or epigenetic factor, in both the cytoplasm and nucleus functions of the adipose stem cells. 28500728

名称对应

Type IDs
Synonymous PPTA3, Ppt5fl, RATPPTA3, TAC
Gene
UniProtKB-ID: TKN1_RAT
UniprotKB: P06767
UniParc: UPI000002B55F, UPI000002B561, UPI0000136FCF, UPI000002B560
EMBL: M34183, M34184, M15191, M14312, M34159, X56306, M34160, S72369, M34161, M34162, L07328
Ensembl: ENSRNOG00000007374
KO: rno:24806
Nucleutide sequences
EMBL-CDS: AAA41927.1, CAA39752.1, AAB31499.1, AAA41926.1, AAA41924.1, AAA41928.1, AAA41929.1, AAA41925.1
Ensembl_TRS: ENSRNOT00000052333, ENSRNOT00000009888, ENSRNOT00000034719
Protein sequencees
Ensembl_PRO: ENSRNOP00000048764, ENSRNOP00000033246, ENSRNOP00000009888
RefSeq: NP_001118240.1, NP_001118241.1, NP_001118242.1, NP_036798.1
Others
UniRef100: UniRef100_P06767
UniRef90: UniRef90_P20366
UniRef50: UniRef50_P20366
UniGene: Rn.1920

全选

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