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24786 Sod1

24786

Sod1

superoxide dismutase 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition superoxide dismutase 1

研究结论

Date Results Publications
2019-06-29 10:07:00 In rat primary microglia the overexpression of the most-common SOD1 mutations linked to familial amyotrophic lateral sclerosis (G93A and A4V) leads to SOD1 intracellular accumulation, which correlates to autophagy dysfunction and microglial activation. 30315929
2019-03-16 10:25:00 The mutant overexpressed SOD1(G93A) protein does not properly bind zinc in spinal cord tissue. 29299811
2018-06-30 11:38:00 These results indicate that stress conditions most probably altered the cell redox equilibrium, thus influencing the antioxidant response in brain cortex. 29847079
2018-05-26 11:11:00 Results provide evidence that ALS mutant SOD1 inhibits axonal transport of mitochondria by inducing PINK1/Parkin-dependent Miro1 degradation. 28973175
2018-05-05 10:34:00 SOD1 protein expression is upregulated and associated with greater oxidant production in skeletal muscle from Ts65Dn mice. 28697486

名称对应

Type IDs
Synonymous CuZnSOD
Gene
UniProtKB-ID: SODC_RAT
UniprotKB: P07632
UniParc: UPI0000167A90
EMBL: Y00404, BC082800, Z21917, M25157, Z21919, Z21918, X05634, Z21920
Ensembl: ENSRNOG00000002115
KO: rno:24786
Nucleutide sequences
EMBL-CDS: AAA42160.1, CAA68465.1, CAA79925.1, CAA29121.1, AAH82800.1
Ensembl_TRS: ENSRNOT00000002885
Protein sequencees
Ensembl_PRO: ENSRNOP00000002885
RefSeq: NP_058746.1
Others
UniRef100: UniRef100_P07632
UniRef90: UniRef90_P08228
UniRef50: UniRef50_P08228
UniGene: Rn.6059

全选

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研究热度

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