| Type | Description |
|---|---|
| Definition | surfactant protein A1 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-17 12:08:00 | SP-A expression was up-regulated in the middle ear effusion of non-typeable Haemophilus influenza otitis media. | 30055742 |
| 2017-08-19 10:38:00 | binds dipalmitoyl-phosphatidylcholine, the major surfactant lipid component, but not phosphatidylinositol; SPD exhibits the opposite preference. Data suggest flexibility in a key surface loop supports distinctive lipid binding of quadruple mutant duanyu1842 (E171D/P175E/R197N/K203D) that introduces SPD-like loop-stabilizing Ca2+ binding site in carbohydrate recognition domain exhibits ligand-binding preferences of SPD. | 28719181 |
| 2017-07-01 13:01:00 | Downregulation of SP-A expression caused due to silica is an important factor in the occurrence and development of silicosis. | 27660222 |
| 2015-12-19 11:41:00 | Liraglutide activates the GLP1 receptor, increasing ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of Type 1 Diabetes rats | 26196539 |
| 2015-01-31 12:20:00 | Mutations of rat surfactant protein A have distinct effects on its glycosylation, secretion, aggregation and degradation. | 25242514 |
| Type | IDs |
|---|---|
| Synonymous | PSAP, PSP-A, SP-A, Sftp1, Sftpa, Sftpl |
| Gene |
UniProtKB-ID:
SFTPA_RAT
UniprotKB:
P08427
UniParc:
UPI00001327F1
EMBL:
M15754,
X13176,
U43092,
BC085353,
X13177,
M33201
Ensembl:
ENSRNOG00000011438
KO:
rno:24773
|
| Nucleutide sequences |
EMBL-CDS:
CAA31574.1,
AAA41972.1,
AAH85353.1,
AAA85516.1,
AAA41973.1,
CAA31573.1
Ensembl_TRS:
ENSRNOT00000047870
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000039850
RefSeq:
NP_059025.2,
NP_001257576.1,
NP_001257574.1
|
| Others |
UniRef100:
UniRef100_P08427
UniRef90:
UniRef90_P08427
UniRef50:
UniRef50_Q8IWL2
UniGene:
Rn.11343
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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