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24718 Reln

24718

Reln

reelin

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition reelin

研究结论

Date Results Publications
2020-03-14 12:26:00 in diabetic rats, diabetes reduced the spatial memory without altering the reelin levels while exercise improved spatial memory without altering the reelin levels 32115961
2019-10-12 12:50:00 data provide evidence of a local increase of aromatase expression by reelin. Regarding reproduction, this crosstalk may contribute to follicular stability and counteract luteinization in ovaries. 29880879
2019-08-31 10:23:00 Maternal deprivation (MD) enhanced contextual fear memory in adulthood. Meanwhile, MD decreased DNA methyltransferase mRNA and Reelin gene methylation in the hippocampal CA1 on postnatal days 22 and 90. Reelin protein expression was increased in the hippocampal CA1 following contextual fear conditioning in adulthood. MD can epigenetically program second-hit stress-induced Reelin expression. 30169690
2018-05-26 10:57:00 Study found that reelin levels in the visual layers of the superior colliculus are the highest between the second and third postnatal weeks. Blocking reelin signaling with a neutralizing antibody (CR-50) from PND 7 to PND 14 induced a non-specific sprouting of ipsilateral retinocollicular axons outside their typical distribution of discrete patches of axon terminals. 28602919
2018-03-31 10:12:00 Melatonin ameliorated the neurotoxiciy and astrocyte activation induced by Abeta1-42 in the cerebral cortex. Melatonin also blocked the reduction in Reelin and Dab1 expression induced by Abeta1-42. Using in vitro study, Reelin inactivation completely abolished the protective effect of melatonin against Abeta1-42-induced neurotoxicity. 28385118

名称对应

Type IDs
Synonymous Reelen, Rl, reeler
Gene
UniProtKB-ID: RELN_RAT
UniprotKB: P58751
UniParc: UPI000002B23B, UPI000013366C, UPI000002B23C
EMBL: AB062680, AB049473
KO: rno:24718
Nucleutide sequences
EMBL-CDS: BAC75467.1, BAB78470.1
Protein sequencees
RefSeq: XP_006235935.1, NP_536319.3, XP_017447961.1
Others
UniRef100: UniRef100_P58751
UniRef90: UniRef90_Q60841
UniRef50: UniRef50_Q60841
UniGene: Rn.98353

全选

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