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246774 Gimap5

246774

Gimap5

GTPase, IMAP family member 5

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition GTPase, IMAP family member 5

研究结论

Date Results Publications
2017-08-19 12:10:00 These findings confirm a critical albeit differential role of T-cell lymphopenia in the susceptibility to organ-specific autoimmune responses. 26740263
2016-09-03 11:37:00 functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells. 27023180
2013-03-30 12:18:00 Data indicate that reduced Ca2+ influx in GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5)-deficient T-cells is associated with the inability of their mitochondria to sequester Ca2+ following capacitative entry. 23098229
2011-12-03 11:22:00 results suggest that lack of the Gimap5 protein in the DR.(lyp/lyp) congenic rat was associated with impaired expression of the entire family of Gimap genes and may regulate T cell homeostasis in the peripheral lymphoid organs. 21925515
2010-06-14 11:28:00 Obesity and type 2 diabetes in the BioBreeding diabetes-resistant (BBDR) rat result in islet expansion associated with protection from T1D in female but not male BBDR(lepr-/lepr-,Gimap5-/Gimap5-) congenic rats. 19996157

名称对应

Type IDs
Synonymous IAN4, Ian4l1, Ian5, lyp
Gene
UniProtKB-ID: GIMA5_RAT, Q0R3W7_RAT
UniprotKB: Q8K3L6, Q0R3W7
UniParc: UPI00000E8371, UPI00000E5C93
EMBL: CH474011, AY055776, BC092561, AY550021, AY055777, AY550023, AY550018, AY550019, AY550022, AY550020, DQ125352
Ensembl: ENSRNOG00000008416
KO: rno:246774
Nucleutide sequences
EMBL-CDS: AAS56934.1, AAL17699.2, AAH92561.1, AAL17698.1, AAS56938.1, AAS56933.1, AAS56935.1, AAS56936.1, AAS56937.1, ABB03709.1, EDL88238.1
Gene_ORFName: rCG_52319
Ensembl_TRS: ENSRNOT00000084927, ENSRNOT00000059156
Protein sequencees
Ensembl_PRO: ENSRNOP00000072663, ENSRNOP00000055929
RefSeq: NP_663713.1, XP_008761093.1, XP_006236519.1, NP_001029085.1, XP_006236520.1
Others
UniRef100: UniRef100_Q8K3L6, UniRef100_Q0R3W7
UniRef90: UniRef90_Q8K3L6
UniRef50: UniRef50_Q8K3L6
UniGene: Rn.83549

全选

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