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246730 Oas1a

246730

Oas1a

2'-5' oligoadenylate synthetase 1A

protein-coding

Mus musculus

基因描述

Type Description
Definition 2'-5' oligoadenylate synthetase 1A

研究结论

Date Results Publications
2016-07-30 11:44:00 Thus, activation of RNase L does not require mouse hepatitis virus virus-induced interferon but rather correlates with adequate levels of basal Oas gene expression, maintained by basal interferon signaling. 26739051
2012-10-13 10:14:00 Mouse hepatitis virus Ns2 cleaves 2',5'-oligoadenylate, the product of 2',5'-oligoadenylate synthetase, to prevent activation of the cellular endoribonuclease RNase L and consequently block viral RNA degradation. 22704621
2012-04-14 10:48:00 Activation of Oas1a gene expression by type I IFN requires both and 22305621
2010-01-21 00:00:00 In the absence of a functional OAS1a pathway, herpes simplex virus type 1 antigen expression is more widespread, and the ability of IFN-beta transgene treatment to reduce infectious HSV-1 in eyes and trigeminal ganglia is lost. 16002711

名称对应

Type IDs
Synonymous L3
Gene
UniProtKB-ID: OAS1A_MOUSE
UniprotKB: P11928
UniParc: UPI000005339B
EMBL: X04958, M33863, AK149613, AC015535, CH466529, BC013715, X58077, BC057878
Ensembl: ENSMUSG00000052776
KO: mmu:246730
Nucleutide sequences
EMBL-CDS: BAE28990.1, CAA28620.1, AAH57878.1, AAH13715.1, EDL19743.1, CAA41105.1, AAA37116.1
Ensembl_TRS: ENSMUST00000080322
Protein sequencees
Ensembl_PRO: ENSMUSP00000079198
RefSeq: XP_006530393.2, NP_660212.2
Others
UniRef100: UniRef100_P11928
UniRef90: UniRef90_P11928
UniRef50: UniRef50_P11928
UniGene: Mm.14301
CCDS: CCDS19630.1

全选

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研究热度

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