| Type | Description |
|---|---|
| Definition | 2'-5' oligoadenylate synthetase 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-18 10:56:00 | A non-synonymous mutation in Oas2 (I405N) in the viral sensor Oas2 was found and the mutation caused post-partum failure of lactation in healthy mice with otherwise normally developed mammary glands, characterized by greatly reduced milk protein synthesis coupled with epithelial cell death, inhibition of proliferation and a robust interferon response. The mutation activates the OAS2 pathway. | 29117179 |
| Type | IDs |
|---|---|
| Synonymous | Oasl11 |
| Gene |
UniProtKB-ID:
OAS2_MOUSE
UniprotKB:
E9Q9A9
UniParc:
UPI0000026005,
UPI0000194C62
EMBL:
AB067535,
AF418010,
CH466529,
AC115937
Ensembl:
ENSMUSG00000032690
KO:
mmu:246728
|
| Nucleutide sequences |
EMBL-CDS:
EDL19753.1,
AAM54499.1,
BAB84135.1
Ensembl_TRS:
ENSMUST00000081491,
ENSMUST00000053909
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080209,
ENSMUSP00000060082
RefSeq:
NP_001334377.1,
NP_660262.2,
XP_036021033.1
|
| Others |
UniRef100:
UniRef100_E9Q9A9
UniRef90:
UniRef90_E9Q9A9
UniRef50:
UniRef50_P29728
UniGene:
Mm.260926
CCDS:
CCDS19625.2,
CCDS84949.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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