| Type | Description |
|---|---|
| Definition | phospholipase C beta 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-05 12:01:00 | results present a model in which the transient high expression of PLCbeta1 that occurs at the onset of differentiation arrests cells in the G1 phase through its association with CDK16 and allows CDK16 to transition to its postmitotic function of neurite outgrowth and trafficking of synaptic vesicles. | 29401590 |
| 2017-09-30 11:51:00 | PLCbeta through its ability to bind TRAX plays a key role in switching PC12 cells to their differentiated state. | 27624933 |
| 2017-08-05 10:32:00 | Enhanced activation of protein kinase C delta in vascular smooth muscle cell (VSMC) from hypertensive rats (SHR) increases the expression of G alpha protein q (Gqalpha) and phospholipase C beta1 (PLCbeta1) proteins and results in VSMC hypertrophy. | 27379421 |
| 2016-09-24 11:26:00 | down-regulation of gamma-synuclein reduces the protein level of PLCbeta but increases the transcript level over 40 fold | 26521046 |
| 2016-07-16 11:36:00 | Enhanced oxidative stress in VSMCs from SHRs activates c-Src, growth factor receptors and MAPK signaling, contributing to enhanced expression of Gqalpha/PLCbeta1 proteins and VSMC hypertrophy. | 26747500 |
| Type | IDs |
|---|---|
| Synonymous | PLC'1, PLCbeta1, Phosphb, RATPHOSPHB |
| Gene |
UniProtKB-ID:
PLCB1_RAT
UniprotKB:
P10687
UniParc:
UPI0000131A90
EMBL:
M20636
KO:
rno:24654
|
| Nucleutide sequences |
EMBL-CDS:
AAA41885.1
|
| Protein sequencees |
RefSeq:
XP_017446955.1,
NP_001071109.1,
XP_017446956.1
|
| Others |
UniRef100:
UniRef100_P10687
UniRef90:
UniRef90_P10687
UniRef50:
UniRef50_Q9Z1B3
UniGene:
Rn.45523
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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