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246538 Sema2b

246538

Sema2b

Semaphorin 2b

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Semaphorin 2b

研究结论

Date Results Publications
2020-04-11 10:52:00 Secreted semaphorin 2b (Sema-2b) acts through its transmembrane receptor Plexin B (PlexB) to locally attract neural processes to specific fan-shaped body (FB) laminae. Aberrant Sema-2b/PlexB signaling leads to select disruptions in neural lamination, and these disruptions result in the formation of ectopic inhibitory connections between subsets of FB neurons. 31564592
2018-03-03 11:56:00 semaphorin 2b is a target-derived signal that acts upon presynaptic plexin B receptors to mediate the retrograde, homeostatic control of presynaptic neurotransmitter release at the neuromuscular junction in Drosophila; Sema2b-PlexB signalling regulates presynaptic homeostatic plasticity through the cytoplasmic protein Mical and the oxoreductase-dependent control of presynaptic actin 28953869
2016-07-02 10:37:00 This study showed that mutations in the semaphorin ligand sema-2b lead to a dramatic increase in self-crossing of dendrites due to defects in dendrite-extracellular matrix adhesion. 26853303
2013-08-10 11:51:00 Sema-2b couples olfactory receptor neuron axon guidance to postsynaptic target neuron dendrite patterning well before the final target selection phase. 23719164

名称对应

Type IDs
Synonymous CG30322, CG33960, CG4383, Dmel\CG33960, Sema-2b, SemaIIB, sema-2b, sema2b
Gene
UniProtKB-ID: Q29QV5_DROME, A1ZAF5_DROME, A0A0B4KG38_DROME
UniprotKB: Q29QV5, A1ZAF5, A0A0B4KG38
UniParc: UPI000066E69B, UPI00029465B9, UPI00006C6B04
EMBL: BT024285, BT133256, AE013599
EnsemblGenome: FBgn0264273
KO: dme:Dmel_CG33960
Nucleutide sequences
EMBL-CDS: ACL83134.1, ABC86347.1, AAM68522.2, AFC17500.1, AGB93557.1, AGB93556.1
Gene_ORFName: CG33960, Dmel_CG33960, Dmel_CG33960, CG33960, Dmel_CG33960, CG33960
EnsemblGenome_TRS: FBtr0290009, FBtr0329991, FBtr0100001, FBtr0329992
Protein sequencees
EnsemblGenome_PRO: FBpp0288448, FBpp0099865, FBpp0303026, FBpp0303027
RefSeq: NP_001261025.1, NP_001261024.1, NP_001033952.1, NP_001137680.1
Others
UniRef100: UniRef100_A0A0B4KG38, UniRef100_A1ZAF5
UniRef90: UniRef90_A0A0B4KG38
UniRef50: UniRef50_A0A0B4KG38
UniGene: Dm.16007

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