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24650 Pkd1

24650

Pkd1

polycystin 1, transient receptor potential channel interacting

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition polycystin 1, transient receptor potential channel interacting

研究结论

Date Results Publications
2021-04-17 13:12:00 Polycystin-1 mitigates damage and regulates CTGF expression through AKT activation during cardiac ischemia/reperfusion. 33065236
2019-02-23 12:28:00 PKD1 enhances the stability of N-cadherin on cell membrane and promotes synapse morphogenesis and synaptic plasticity in an activity-dependent manner 29133434
2018-08-18 10:05:00 PKD1 mediates the effects on KV11.1 and we found that PKD targets S284 in the N-terminus of the channel. 29949809
2018-04-21 10:12:00 These findings provide novel evidence that PC1 is involved in the regulation of cardiac LTCCs through a Gibetagamma-AKT-Cavbeta2 pathway, suggesting a new mechanism for regulation of cardiac function. 29126879
2017-06-24 11:35:00 PAK-mediated phosphorylation of PKD1 at Ser203 triggers its membrane dissociation and subsequent entry into the nucleus, thereby regulating the phosphorylation of PKD1 nuclear targets, including class IIa histone deacetylases. 28408623

名称对应

Type IDs
Gene
UniProtKB-ID: F1MAD3_RAT
UniprotKB: F1MAD3
UniParc: UPI0000251D5F
EMBL: AC093937
Ensembl: ENSRNOG00000010771
KO: rno:24650
Nucleutide sequences
Ensembl_TRS: ENSRNOT00000015092
Protein sequencees
Ensembl_PRO: ENSRNOP00000015092
RefSeq: XP_008765763.1, NP_001244281.1, XP_008765760.1, XP_008765761.1, XP_008765762.1
Others
UniRef100: UniRef100_F1MAD3
UniRef90: UniRef90_F1MAD3
UniRef50: UniRef50_P98161
UniGene: Rn.127770

全选

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研究热度

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