| Type | Description |
|---|---|
| Definition | Pim-1 proto-oncogene, serine/threonine kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:31:00 | PIM1 phosphorylates KU70 and initiates DNA repair signaling in pulmonary artery hypertension-pulmonary artery smooth muscle cells. PIM1 inhibitors represent a therapeutic option for patients with PAH. | 31969012 |
| 2019-10-26 12:15:00 | Overexpression of Pim1 in retinal ganglion cells is related to optic nerve repair following optic nerve crush. | 30299595 |
| 2018-10-27 11:25:00 | Pim1 overexpression prevented NRVM apoptosis via upregulation of autophagy after hypoxia and oxidative stress, partly via activation of the AMPK/mTOR/ATG5 autophagy pathway. | 30257237 |
| 2018-06-23 10:45:00 | Pim-1 is a novel kinase that phosphorylates cTnI primarily at Ser23/24 and Ser150 in cardiomyocytes, which in turn may modulate myofilament function under a variety of physiological and pathophysiological conditions. | 29544221 |
| 2016-12-17 10:07:00 | Hypoxic preconditioning could increase short-term survival of bone marrow mesenchymal stem cells via upregulation of Pim-1, and miR-206 was one of the critical regulators in this process. | 27103465 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PIM1_RAT
UniprotKB:
P26794
UniParc:
UPI0000131AD6
EMBL:
X63675
Ensembl:
ENSRNOG00000000529
KO:
rno:24649
|
| Nucleutide sequences |
EMBL-CDS:
CAA45214.1
Ensembl_TRS:
ENSRNOT00000000637
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000000637
RefSeq:
NP_058730.1
|
| Others |
UniRef100:
UniRef100_P26794
UniRef90:
UniRef90_P26794
UniRef50:
UniRef50_P26794
UniGene:
Rn.34888
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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