| Type | Description |
|---|---|
| Definition | pellino E3 ubiquitin protein ligase family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:04:00 | PELI3 gene expression in blood and ovarian cancer. | 31520466 |
| 2017-07-29 10:59:00 | Two protective, low-frequency, non-synonymous variants were significantly associated with a decrease in age-related macular degeneration (AMD)risk: A307V in PELI3 and N1050Y in CFH .We also identified a strong protective signal for a common variant (rs8056814) near CTRB1 associated with a decrease in AMD risk (logistic regression: OR = 0.71, P = 1.8 x 10-07). | 28011711 |
| 2017-02-18 12:12:00 | The combination of low Pellino3 levels together with high and inducible Pellino1 expression may be an important determinant of the degree of inflammation triggered upon Toll-like receptor 2 engagement by Helicobacter pylori and/or its components, contributing to Helicobacter pylori-associated pathogenesis by directing the incoming signal toward an NF-kB-mediated proinflammatory response. | 27302665 |
| 2016-03-26 11:48:00 | Pellino-3 is involved in endotoxin tolerance and functions as a negative regulator of Toll-like receptor 2/4 signaling. | 26310831 |
| 2014-09-27 12:05:00 | Peptide PEL3 derived from the interleukin-1 receptor-associated kinase (IRAK)1-binding motif reveals a distinct phosphothreonine peptide binding preference. | 25027698 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PELI3_HUMAN,
A0A024R5B1_HUMAN,
A0A024R5I2_HUMAN
UniprotKB:
Q8N2H9,
A0A024R5B1,
A0A024R5I2
UniParc:
UPI00000707EF,
UPI00000443BA,
UPI00001BDA75,
UPI000007324B
EMBL:
AK075253,
AK094060,
AK074201,
AF487457,
CH471076,
BC025723,
AL834395,
AF487456,
BC021256
Ensembl:
ENSG00000174516
KO:
hsa:246330
|
| Nucleutide sequences |
EMBL-CDS:
BAC04275.1,
AAH21256.1,
AAO49466.1,
BAB85015.1,
AAO49465.1,
CAD39057.1,
BAC11499.1,
AAH25723.1,
EAW74532.1,
EAW74536.1,
EAW74534.1,
EAW74533.1
Gene_ORFName:
hCG_20665,
hCG_20665
Ensembl_TRS:
ENST00000524466,
ENST00000320740,
ENST00000349459,
ENST00000618547
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000309848,
ENSP00000322532,
ENSP00000484220,
ENSP00000434677
RefSeq:
XP_016872954.1,
NP_001230065.1,
NP_001230064.1,
XP_011543186.1,
NP_001091980.1,
NP_659502.2
|
| Others |
UniRef100:
UniRef100_A0A024R5I2,
UniRef100_Q8N2H9
UniRef90:
UniRef90_Q8BXR6,
UniRef90_Q8N2H9
UniRef50:
UniRef50_Q8BXR6,
UniRef50_Q8N2H9
UniGene:
Hs.656875
CCDS:
CCDS73328.1,
CCDS41675.1,
CCDS31615.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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