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246294 Optn

246294

Optn

optineurin

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition optineurin

研究结论

Date Results Publications
2019-01-05 10:04:00 Overexpression of E50K-mutated optineurin triggered BDNF deficiency, leading to Bax activation in a retinal photoreceptor cell line. 30100066
2015-06-27 13:51:00 optineurin appears to play an important role in the maintenance of the podocyte Golgi complex. 25096716
2011-03-26 12:10:00 in a normal homeostatic situation, the turnover of endogenous optineurin involves mainly ubiquitin-proteasome pathway (UPP). When optineurin is up-regulated or mutated, the UPP function is compromised, and autophagy comes into play. 21059646
2010-03-22 11:56:00 These results demonstrated that the two glaucoma genes, myocilin and optineurin, exhibited differential effects on neurite outgrowth. 19959812
2010-01-21 00:00:00 mGLuR1a signaling is attenuated by the huntingtin-binding protein optineurin 16091361

名称对应

Type IDs
Synonymous Fip2
Gene
UniProtKB-ID: OPTN_RAT, A0A0G2JUB3_RAT
UniprotKB: Q8R5M4, A0A0G2JUB3
UniParc: UPI00004EACC7, UPI00004966F5, UPI000019C077
EMBL: AC105577, AB069907, BC086976
Ensembl: ENSRNOG00000017941
KO: rno:246294
Nucleutide sequences
EMBL-CDS: BAB84696.2, AAH86976.1
Ensembl_TRS: ENSRNOT00000083342
Protein sequencees
Ensembl_PRO: ENSRNOP00000069034
RefSeq: XP_006254324.1, XP_017455943.1, XP_017455944.1, XP_006254326.1, XP_006254325.1, NP_659549.3
Others
UniRef100: UniRef100_Q8R5M4, UniRef100_A0A0G2JUB3
UniRef90: UniRef90_Q8R5M4
UniRef50: UniRef50_Q96CV9
UniGene: Rn.63435

全选

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研究热度

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