| Type | Description |
|---|---|
| Definition | AFG1 like ATPase |
| Date | Results | Publications |
|---|---|---|
| 2018-03-03 11:32:00 | Increased expression of LACE1 partitions p53 to mitochondria, causes reduction in nuclear p53 content and induces apoptosis. Thus, LACE1 mediates mitochondrial translocation of p53 and its transcription-independent apoptosis. | 27323408 |
| 2016-08-13 11:53:00 | This study establishes LACE1 as a novel factor with a crucial role in mitochondrial protein homeostasis. | 26759378 |
| 2011-01-15 11:27:00 | association between bipolar disorder and two SNPs in the gene LACE1 | 20872768 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| Type | IDs |
|---|---|
| Synonymous | AFG1, LACE1, c222389 |
| Gene |
UniProtKB-ID:
AFG1L_HUMAN
UniprotKB:
Q8WV93
UniParc:
UPI0000072226
EMBL:
BC018445,
AL353706,
Z98742,
AL139106,
AF520418,
AL356121
Ensembl:
ENSG00000135537
KO:
hsa:246269
|
| Nucleutide sequences |
EMBL-CDS:
AAM74228.1,
AAH18445.2
Ensembl_TRS:
ENST00000368977
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357973
RefSeq:
XP_016866138.1,
NP_001309934.1,
XP_011533962.1,
XP_016866137.1,
NP_660358.2,
XP_024302159.1,
XP_011533961.1,
XP_005266942.1,
XP_016866136.1,
XP_011533963.1,
XP_011533959.1
|
| Others |
UniRef100:
UniRef100_Q8WV93
UniRef90:
UniRef90_Q8WV93
UniRef50:
UniRef50_Q8WV93
UniGene:
Hs.259666
CCDS:
CCDS5067.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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