Type | Description |
---|---|
Definition | phosphodiesterase 4B |
Date | Results | Publications |
---|---|---|
2019-07-20 12:57:00 | PDE4B is primarily responsible for muscle proteolysis in burn injury and it, thus, constitutes a unique target for selective manipulations with drugs to control muscle cachexia. | 29693432 |
2019-05-25 12:06:00 | The mRNA expression of PDE4D was significantly increased in allergic rats, but PDE4B was not. PDE4B was mainly distributed in the cytoplasm, whereas PDE4D was mainly distributed in the cell membrane | 30628641 |
2014-11-08 13:45:00 | PDE4B mediates a crucial feedback that controls beta1 adrenergic receptor-dependent cAMP signals in a restricted subsarcolemmal domain. | 24413164 |
2013-11-30 10:37:00 | Upregulated PDE4 expression during cholestatic liver injury plays a potential pathogenic role in the development of inflammation and fibrosis. | 23887098 |
2013-08-10 11:14:00 | Acutely after spinal cord injury, PDE4B is localized to activated microglia and is absent in uninjured spinal cord or inactive microglia. | 22865690 |
Type | IDs |
---|---|
Synonymous | PDE4/IVb, Pde4B1, Pde4B2, Pde4B3, Pde4B4, Pde4b5, Pde4b_v1, Pde4b_v2, Pde4b_v3, Pde4b_v4 |
Gene |
UniProtKB-ID:
PDE4B_RAT
UniprotKB:
P14646
UniParc:
UPI000002A6D9,
UPI0000127BF7,
UPI000156545E,
UPI0001565464,
UPI0001565463
EMBL:
U95748,
AF202733,
U01291,
J04563,
U01296,
U01295,
L27058,
U01293,
AF202732,
M28413,
U01289,
U01298,
U01294,
U01297,
BC085704,
U01290,
M25350
Ensembl:
ENSRNOG00000005905
KO:
rno:24626
|
Nucleutide sequences |
EMBL-CDS:
AAA74478.1,
AAA66039.1,
AAA41846.1,
AAL31763.1,
AAA41824.1,
AAH85704.1,
AAA18926.1,
AAB96560.1,
AAL31764.1
Ensembl_TRS:
ENSRNOT00000007738
|
Protein sequencees |
Ensembl_PRO:
ENSRNOP00000007738
RefSeq:
NP_058727.3
|
Others |
UniRef100:
UniRef100_P14646
UniRef90:
UniRef90_Q07343
UniRef50:
UniRef50_Q07343
UniGene:
Rn.37733
|
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