| Type | Description |
|---|---|
| Definition | receptor-interacting serine-threonine kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:54:00 | Heat stress induces RIP1/RIP3-dependent necroptosis through the MAPK, NF-kappaB, and c-Jun signaling pathways in pulmonary vascular endothelial cells. | 32471717 |
| 2020-05-16 12:13:00 | data may identify Ripk3 upregulation, mitochondrial dysfunction and JNK-Bnip3 axis activation as the novel mechanisms underlying cardiomyocytes necrosis achieved by hypoxia-reoxygenation injury | 31658855 |
| 2020-03-28 11:36:00 | our findings indicated that RIP3 contributed to brain damage after subarachnoid hemorrhage by inducing necroptosis | 31082470 |
| 2019-03-16 10:38:00 | Data indicate the role of receptor interacting protein 3 (RIP3) in cardiomyocyte injury during hypoxia/reoxygenation (H/R), suggesting RIP3 may serve as a potential target for the treatment of myocardial ischemia-reperfusion injury (MIRI). | 30215665 |
| 2018-05-26 10:18:00 | Data found another important signaling pathway of RIP3 in the nucleus in the neuronal programmed necrosis induced by cerebral ischemia/reperfusion (I/R) injury. The formation of a RIP3-AIF complex and its nuclear translocation are critical to ischemic neuronal DNA degradation and programmed necrosis. | 27377128 |
| Type | IDs |
|---|---|
| Synonymous | Hcyp2, Rip3 |
| Gene |
UniProtKB-ID:
RIPK3_RAT
UniprotKB:
Q9Z2P5
UniParc:
UPI0000038D08
EMBL:
AABR06083269,
AF036537,
CH474049,
BC158580
Ensembl:
ENSRNOG00000020465
KO:
rno:246240
|
| Nucleutide sequences |
EMBL-CDS:
EDM14286.1,
AAI58581.1,
EDM14285.1,
AAD02059.2
Ensembl_TRS:
ENSRNOT00000027759
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000027759
RefSeq:
NP_647558.1
|
| Others |
UniRef100:
UniRef100_Q9Z2P5
UniRef90:
UniRef90_Q9Z2P5
UniRef50:
UniRef50_Q9Z2P5
UniGene:
Rn.7110
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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