| Type | Description |
|---|---|
| Definition | VPS54 GARP complex subunit |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 10:28:00 | UBPy-sorted cargo to acrosome biogenesis and effects of its derailment in a mouse model of globozoospermia, the infertile Vps54 (L967Q) mutant, are reported. | 28299521 |
| 2016-07-30 10:28:00 | This study demonstrated that the cerebellum is affected by neurodegenerative and inflammatory processes in the Wobbler mouse model of ALS. | 26945034 |
| 2015-06-27 14:19:00 | Investigation of cells derived from wobbler and Vps54 null mutant embryos demonstrates impaired retrograde transport of the Cholera-toxin B subunit to the trans-Golgi network and mis-sorting of mannose-6-phosphate receptors and cargo proteins. | 23708095 |
| 2014-11-22 11:02:00 | We conclude that a missense mutation in VPS54, an essential component of the Golgi-associated retrograde protein complex, not only prevents the formation of an acrosome but also initiates a cascade of metabolic abnormalities and a stress reaction. | 24115398 |
| 2010-09-06 12:15:00 | Severely reduced levels of mutant Vps54 and, consequently, of the whole complex underlie the phenotype of the wobbler mouse. | 20615984 |
| Type | IDs |
|---|---|
| Synonymous | Hcc8, Vps54l, mSLP8, wr |
| Gene |
UniProtKB-ID:
VPS54_MOUSE,
Q91ZJ4_MOUSE
UniprotKB:
Q5SPW0,
Q91ZJ4
UniParc:
UPI0000020F2F,
UPI00000E8F50,
UPI0000253849
EMBL:
AK077306,
BC025012,
AL669979,
BC023474,
AB052761,
BC024789,
AL833772,
AF424699
Ensembl:
ENSMUSG00000020128
KO:
mmu:245944
|
| Nucleutide sequences |
EMBL-CDS:
BAC53794.1,
AAH25012.1,
AAH23474.1,
AAH24789.1,
BAC36741.1,
AAL24808.2
Ensembl_TRS:
ENSMUST00000109578,
ENSMUST00000006221
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006221,
ENSMUSP00000105206
RefSeq:
XP_011242022.1,
NP_620692.3,
NP_001277557.1,
XP_006514762.1,
XP_030101864.1
|
| Others |
UniRef100:
UniRef100_Q91ZJ4,
UniRef100_Q5SPW0
UniRef90:
UniRef90_Q5SPW0,
UniRef90_Q9P1Q0-4
UniRef50:
UniRef50_Q9P1Q0,
UniRef50_Q9P1Q0-4
UniGene:
Mm.170103
CCDS:
CCDS24463.1,
CCDS70147.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员