DEFB106A - defensin beta 106A-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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245909 DEFB106A

基因描述

Type	Description
Definition	defensin beta 106A

研究结论

Date	Results	Publications
2014-12-20 10:06:00	Unique properties of human beta-defensin 6 (hBD6) and glycosaminoglycan complex: sandwich-like dimerization and competition with the chemokine receptor 2 (CCR2) binding site.	24970887
2014-10-28 11:31:00	DEFB106 (also known as DEFB6) displays antimicrobial activity against E. coli, C. albicans and S. aureus.	24189797
2010-01-21 00:00:00	A pilot study with cRNA probes for in situ hybridization and a synthetic propeptide for the functional characterization demonstrated the tissue-/cell-specific expression and the strong antimicrobial activity of DEFB106	12600824
2010-01-21 00:00:00	The epididymis-specific expression pattern of the beta-defensin isoform BD-6 has been characterized.	12193721
2009-03-25 21:36:00	Observational study of gene-disease association. (HuGE Navigator)	19194307

名称对应

Type	IDs
Synonymous	BD-6, DEFB-6, DEFB106
Gene	UniProtKB-ID: D106A_HUMAN UniprotKB: Q8N104 UniParc: UPI0000128D8F EMBL: BC110062, AB089181, BC100844, BC111688, BC100846, AF540978, BC100845, AY122466, AF529417, BC100847 Ensembl: ENSG00000285617, ENSG00000187082, ENSG00000186579, ENSG00000275794 KO: hsa:503841, hsa:245909
Nucleutide sequences	EMBL-CDS: AAI00845.1, AAM93908.1, AAI11689.1, AAI00847.1, BAC10631.1, AAI00846.1, AAN33114.1, AAI00848.1, AAI10063.1, AAQ09526.1 Ensembl_TRS: ENST00000335186, ENST00000621252, ENST00000650001, ENST00000650390, ENST00000335479
Protein sequencees	Ensembl_PRO: ENSP00000335307, ENSP00000477883, ENSP00000334364, ENSP00000498101, ENSP00000497538 RefSeq: NP_689464.1
Others	UniRef100: UniRef100_Q8N104 UniRef90: UniRef90_Q8N104 UniRef50: UniRef50_Q8N104 UniGene: Hs.535925 CCDS: CCDS34833.1, CCDS34813.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
24970887	Unique properties of human Î²-defensin 6 (hBD6) and glycosaminoglycan complex: sandwich-like dimerization and competition with the chemokine receptor 2 (CCR2) binding site. J. Biol. Chem. Viviane S De Paula , Vitor H Pomin , Ana Paula Valente	2014-08-15	DEFB106A, CCR2
24189797	Soluble fusion expression, characterization and localization of human Î²-defensin 6. Mol Med Rep Aijie Xin , Yue Zhao , Heguo Yu , Huijuan Shi , Haiyan Liu , Hua Diao , Yonglian Zhang	2014-01-01	DEFB106A, DEFB106B
23938203	Structural basis for the interaction of human Î²-defensin 6 and its putative chemokine receptor CCR2 and breast cancer microvesicles. J. Mol. Biol. V S De Paula , N S F Gomes , L G Lima , C A Miyamoto , R Q Monteiro , F C L Almeida , A P Valente	2013-11-15	-
19194307	Copy number variation of defensin genes and HIV infection in Brazilian children. J Acquir Immune Defic Syndr Michele Milanese , Ludovica Segat , Luiz C Arraes , Alfredo Garzino-Demo , Sergio Crovella	2009-03-01	-
16033865	Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Physiol. Genomics Amar A Patil , Yibin Cai , Yongming Sang , Frank Blecha , Guolong Zhang	2005-09-21	Gm6040, Gm15056, Gm17416, Defb19, Defb36, Defb20, Defb50, Defb21, Defb48, Defb45, Defb22, Defb28, Spag11b, Defb46, Defb42, Defb23, Defa-ps12, Defb33, Defb44-ps, Gm21944, Defa-ps13, Defb26, Defb43, Defb25, Defb18, Gm15386, Defb47, Defb30, Defb41, Spag11a, Defb22, Defb52, Defb29, Defb51, Defb23, Defb16-ps, Defb3, Defb5, Defb13, Defb14, Defb28, Defb26, Defb11, Defb2, Defb24, Defb9, Defb19, Defb10, Defb21, Defb40, Defb50, Defb36, Defb20, Defb27, Defb12, Defb25, Defb15, Defb39, Defb33, Defb41, Defb43, Defb44, Defb49, Defb18, Defb30, Defb42, Defb17, Defb4, Defb37, Defb38, Spag11b, DEFB107A, LOC100170034, DEFB110, DEFB117, DEFB103A, DEFB126, DEFB104, DEFB106A, DEFB105A, DEFB108P, DEFB134, DEFB136, DEFB135, DEFB133, DEFB114, DEFB113, DEFB112, DEFB115, DEFB118, DEFB123, DEFB124, DEFB131, DEFB127, DEFB129, DEFB132, DEFB116, DEFB119, DEFB121
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7
15727258	Evidence for duplication of the human defensin gene DEFB4 in chromosomal region 8p22-23 and implications for the analysis of SNP allele distribution. Genet. Test. Michele Boniotto , Mario Ventura , Joyce Eskdale , Sergio Crovella , Grant Gallagher	2004-09-01	DEFB104A, DEFB4A, DEFB105A, DEFB106A, DEFB107A, DEFB107B, DEFB104B, DEFB106B, DEFB105B
15588320	Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence. BMC Genomics Stefan Taudien , Petra Galgoczy , Klaus Huse , Kathrin Reichwald , Markus Schilhabel , Karol Szafranski , Atsushi Shimizu , Shuichi Asakawa , Adam Frankish , Ivan F Loncarevic , Nobuyoshi Shimizu , Roman Siddiqui , Matthias Platzer	2004-01-01	DEFB104A, DEFT1P, DEFB105A, DEFB106A, DEFB107A, DEFA8P, DEFA9P, DEFB107B, DEFB104B, DEFB106B, DEFB105B, DEFA1A3, DEFA7P, DEFA11P
12916016	Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster. Am. J. Hum. Genet. E J Hollox , J A L Armour , J C K Barber	2003-09-01	-
12600824	ORFeome-based search of airway epithelial cell-specific novel human [beta]-defensin genes. Am. J. Respir. Cell Mol. Biol. Cheng Yuan Kao , Yin Chen , Yu Hua Zhao , Reen Wu	2003-07-01	DEFB118, DEFB129, DEFB106A, DEFB108B, DEFB109P1, DEFB131

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