| Type | Description |
|---|---|
| Definition | neurite extension and migration factor |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:12:00 | ale NEXMIF KO mice demonstrate reduced sociability and communication, elevated repetitive grooming behavior, and deficits in learning and memory. Loss of NEXMIF/KIDLIA expression results in a significant decrease in synapse density and synaptic protein expression. Male KO animals show aberrant synaptic function as measured by excitatory miniatures and postsynaptic currents in the hippocampus. | 31704787 |
| 2017-11-04 11:35:00 | Knockdown of KIAA2022/KIDLIA leads to altered neuron migration and a reduction in dendritic growth and disorganized apical dendrite projections in layer II/III cortical neurons. In cultured neurons loss of KIDLIA expression also leads to suppression of dendritic growth and branching. KIDLIA suppression leads to an increase in cell-surface N-cadherin and an elevated association of N-cadherin with delta-catenin. | 27822498 |
| Type | IDs |
|---|---|
| Synonymous | A230051P11, C77370, C77386, KIDLIA, Xpn |
| Gene |
UniProtKB-ID:
NEXMI_MOUSE
UniprotKB:
Q5DTT1
UniParc:
UPI00001C6596,
UPI000058C478
EMBL:
DQ975302,
AL671963,
AK220439,
AK054513,
AK038635
Ensembl:
ENSMUSG00000046449
KO:
mmu:245555
|
| Nucleutide sequences |
EMBL-CDS:
BAC30074.1,
ABI97947.1,
BAD90269.1,
BAC35808.1
Ensembl_TRS:
ENSMUST00000056502,
ENSMUST00000087879,
ENSMUST00000118314
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000085187,
ENSMUSP00000113625,
ENSMUSP00000049716
RefSeq:
XP_006528097.1,
XP_030107199.1,
XP_006528094.1,
NP_001070822.2,
XP_030107200.1
|
| Others |
UniRef100:
UniRef100_Q5DTT1
UniRef90:
UniRef90_Q5DTT1
UniRef50:
UniRef50_Q5QGS0
UniGene:
Mm.381907
CCDS:
CCDS53166.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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