| Type | Description |
|---|---|
| Definition | dyskeratosis congenita 1, dyskerin |
| Date | Results | Publications |
|---|---|---|
| 2013-09-07 10:39:00 | Mouse embryonic fibroblasts cells with no pseudouridylation activity in H/ACA snoRNPs due to lack of Dkc1, can produce mature ribosomes, however, the ribosomes are very unstable and cell growth and division is very slow. | 23726835 |
| 2013-03-16 11:10:00 | mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain. | 22855157 |
| 2010-07-05 11:42:00 | A mouse small nucleolar snoRNA microarray was used to monitor changes in abundance of snoRNAs after ablation of dyskerin, an H/ACA snoRNA protein component, from mouse liver, which causes a decrease in ribosome production. | 20423331 |
| 2010-01-25 11:43:00 | hepatocytes can survive without dyskerin but the role of dyskerin in RNA modification is essential for cellular proliferation. | 19917719 |
| 2010-01-21 00:00:00 | Female mice carrying the deletion in the paternally derived Dkc1 show extreme skewing of X-inactivation with the wild type X-chromosome active in all cells. | 12400016 |
| Type | IDs |
|---|---|
| Synonymous | BC068171 |
| Gene |
UniProtKB-ID:
DKC1_MOUSE
UniprotKB:
Q9ESX5
UniParc:
UPI00001C651D
EMBL:
AJ250975,
AJ250977,
AJ250980,
AJ250976,
AJ250974,
AJ250972,
AJ250973,
AJ250978,
AJ250981,
AJ250979,
AK136418,
AL808110
Ensembl:
ENSMUSG00000031403
KO:
mmu:245474
|
| Nucleutide sequences |
EMBL-CDS:
CAC04528.1,
BAE22970.1
Ensembl_TRS:
ENSMUST00000033776
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033776
RefSeq:
NP_001346340.1,
NP_001346342.1,
NP_001025478.1,
NP_001346341.1,
XP_030107198.1
|
| Others |
UniRef100:
UniRef100_Q9ESX5
UniRef90:
UniRef90_Q9ESX5
UniRef50:
UniRef50_Q9ESX5
UniGene:
Mm.291062
CCDS:
CCDS41029.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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