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24547 Mbp

24547

Mbp

myelin basic protein

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition myelin basic protein

研究结论

Date Results Publications
2020-06-20 10:24:00 All pups with exposure to methadone demonstrated decreased expression of MBP in the cerebral cortex and hippocampus.In the cerebellum, PLP expression was downregulated without apparent alteration of CNP and MBP expression. PLP and MBP expression, but not CNP expression, were significantly inhibited in the brainstem. 31885393
2019-12-28 11:52:00 Gonadectomy prior to puberty onset resulted in a significant reduction of myelin basic protein levels in the orbitofrontal cortex in females but not males. 30926549
2018-12-01 11:23:00 Angiostrongylus cantonensis-conditioned culture medium induced suppression of the Erk1/2-NF-kappaB signaling pathway leading to reduced MBP production in RSC96 Schwann cells. 29742816
2018-06-23 10:39:00 A role for the retrograde dynein/dynactin motor complex in anterograde mbp mRNA transport. 29073112
2017-12-02 11:16:00 The aberrant phase transition of MBP molecules from their cohesive to soluble and non-adhesive state is a mechanism triggering myelin breakdown in neuromyelitis optica. 27346352

名称对应

Type IDs
Synonymous Mbps
Gene
UniProtKB-ID: MBP_RAT, I7FKL4_RAT, Q5XFW1_RAT
UniprotKB: P02688, I7FKL4, Q5XFW1
UniParc: UPI000044F9E0, UPI00000E8214, UPI00005520EC, UPI00001825F8, UPI000018611E, UPI0000163B8F
EMBL: BC094522, AC132699, K00512, AC097762, CH474021, M25889, AJ132895, AF439750, X72392, AJ132896, AJ132898, JX131663, BC084713, AJ132897
Ensembl: ENSRNOG00000016516
KO: rno:24547
Nucleutide sequences
EMBL-CDS: CAA10807.1, CAA10806.1, CAA10805.1, CAA10804.1, AAA41575.1, AAL84189.1, AAH94522.1, AFP20581.1, EDL75209.1, AAH84713.1
Gene_ORFName: rCG_20541
Ensembl_TRS: ENSRNOT00000022280, ENSRNOT00000058296, ENSRNOT00000022303, ENSRNOT00000058295, ENSRNOT00000089879
Protein sequencees
Ensembl_PRO: ENSRNOP00000022280, ENSRNOP00000022303, ENSRNOP00000055098, ENSRNOP00000055097, ENSRNOP00000070157
RefSeq: NP_001020463.1, XP_017456335.1, NP_001020464.1, NP_001020460.1, XP_017456337.1, XP_017456336.1, NP_058722.1, XP_006255059.1, XP_017456334.1, NP_001020465.1, XP_017456338.1, NP_001020462.1
Others
UniRef100: UniRef100_P02688, UniRef100_Q5XFW1
UniRef90: UniRef90_P04370-10, UniRef90_Q5XFW1
UniRef50: UniRef50_P02686-2, UniRef50_P02686
UniGene: Rn.63285

全选

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