| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel subfamily J member 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-26 11:06:00 | Data suggest underlying pathology for some patients with type II Bartter syndrome is linked to stability of ROMK1 in ERAD pathway; using a yeast expression system, cells can be rescued by wild-type (rat) ROMK1 but not by ROMK1 containing any one of four mutations found in (human) type II Bartter syndrome; mutant ROMKs are significantly less stable than wild-type ROMK. (ERAD = endoplasmic reticulum-associated degradation) | 28630040 |
| 2017-08-12 10:25:00 | Blockade of ROMK or Na(+)-K(+)-2Cl(-) transport inhibits tubuloglomerular feedback yet increases renal vascular resistance. The renal vasoconstriction was independent of volume depletion, blood pressure, TGF, or proximal tubule hydrostatic pressure. | 28228405 |
| 2017-06-03 10:25:00 | These preliminary findings suggest that K channel genes play a role in the development of secondary lymphedema | 28252570 |
| 2015-05-16 13:01:00 | Data indicate that mutations in kir1.1 potassium channel preferentially increase pH sensitivity. | 24980796 |
| 2014-04-05 13:48:00 | The TPNQ toxin-rKir1.1 channel complex structure not only revealed their unique interaction mechanism, but also elucidate the relative insensitivity of rKir1.1 channel towards animal toxins. | 23874410 |
| Type | IDs |
|---|---|
| Synonymous | KAB-1, Kcnj, Kcnj1_v1, Kcnj1_v3, ROMK1, ROMK2, ROMK3, kir1.1 |
| Gene |
UniProtKB-ID:
A0A0G2JYW2_RAT
UniprotKB:
A0A0G2JYW2
UniParc:
UPI0001550DB8
EMBL:
AC127149,
CH474007
Ensembl:
ENSRNOG00000059005
|
| Nucleutide sequences |
EMBL-CDS:
EDL83293.1
Gene_ORFName:
rCG_22731
Ensembl_TRS:
ENSRNOT00000081614
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000070813
RefSeq:
XP_008764266.1,
NP_058719.2,
NP_001296228.1,
XP_017450947.1,
NP_001296227.1,
NP_001296230.1,
NP_001296226.1,
XP_008764269.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JYW2
UniRef90:
UniRef90_E2RPY0
UniRef50:
UniRef50_P48048
UniGene:
Rn.22609
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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