| Type | Description |
|---|---|
| Definition | insulin-like growth factor binding protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 10:46:00 | established the molecular roles of IGFBP3, HIF1a, and prolyl hydroxylase domain in connecting oxidative stress with hypoxia and in cellular cardiomyocyte apoptosis under hyperglycemia | 30659610 |
| 2020-04-11 10:49:00 | the inhibition of the ERK/MAPK pathway was mediated by IGFBP3 silencing that had effects on proliferation, apoptosis, autophagy, and cell senescence. | 30370550 |
| 2017-07-22 12:25:00 | Compound 49b treatment inhibited these retinal changes. In REC cultured in hypoxia, levels of IGFBP-3 were reduced, which were significantly increased by Compound 49b. | 27439004 |
| 2016-10-22 10:42:00 | Study indicated that IGFBP-3 shRNA might rehabilitate erectile function via decreased concentrations of serum LDL lipoprotein and triglyceride, increased cavernosal smooth muscle and improvement in NO-cGMP signaling in diabetic rats. | 25879169 |
| 2015-10-31 10:33:00 | IGFBP-3 shRNA may rehabilitate erectile function via increases of concentrations of serum testosterone and cavernous cyclic guanosine monophosphate in streptozotocin-induced diabetic rats | 25582342 |
| Type | IDs |
|---|---|
| Synonymous | IGF-BP3 |
| Gene |
UniProtKB-ID:
IBP3_RAT,
A1A5Q9_RAT
UniprotKB:
P15473,
A1A5Q9
UniParc:
UPI000012D118,
UPI0000EA26D9
EMBL:
BC128764,
M33300,
M31837
KO:
rno:24484
|
| Nucleutide sequences |
EMBL-CDS:
AAB00989.1,
AAA41383.1,
AAI28765.1
|
| Protein sequencees |
RefSeq:
NP_036720.2
|
| Others |
UniRef100:
UniRef100_A1A5Q9,
UniRef100_P15473
UniRef90:
UniRef90_A1A5Q9,
UniRef90_P15473
UniRef50:
UniRef50_P15473,
UniRef50_A1A5Q9
UniGene:
Rn.26369
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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