| Type | Description |
|---|---|
| Definition | lysine (K)-specific demethylase 4D |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:11:00 | Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling. | 32094404 |
| 2020-11-21 13:32:00 | Histone demethylase KDM4D cooperates with NFIB and MLL1 complex to regulate adipogenic differentiation of C3H10T1/2 mesenchymal stem cells. | 32080306 |
| 2019-09-14 13:19:00 | To determine the epigenetic mechanisms limiting CM cycling in adult cardiac myocytes (CMs) (ACMs) and whether trimethylation of lysine 9 of histone H3 (H3K9me3), a histone modification associated with repressed chromatin, is required for the silencing of cell cycle genes, we developed a transgenic mouse model where H3K9me3 is specifically removed in CMs by overexpression of histone demethylase, KDM4D | 29800554 |
| 2019-04-06 12:00:00 | JMJD2D interacts with b-catenin to activate transcription of its target genes and promote CRC cell proliferation, migration, and invasion, as well as formation of colorectal tumors in mice. | 30472235 |
| 2011-10-01 11:03:00 | These results suggest that demethylation of H3K9 in round spermatids is dispensable for spermatogenesis but that possible defects in Kdm4d-null elongating spermatids could be rescued by functional redundancy of the KDM4B demethylase. | 21293030 |
| Type | IDs |
|---|---|
| Synonymous | 4932416A15, Jmjd2d |
| Gene |
UniProtKB-ID:
KDM4D_MOUSE
UniprotKB:
Q3U2K5
UniParc:
UPI0000D72121
EMBL:
AK030020,
BC112372,
CT485607,
AK155227
Ensembl:
ENSMUSG00000053914
KO:
mmu:244694
|
| Nucleutide sequences |
EMBL-CDS:
BAC26740.1,
AAI12373.1,
BAE33135.1
Ensembl_TRS:
ENSMUST00000058796
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000061632
RefSeq:
XP_006510333.1,
NP_775609.2,
XP_006510334.1
|
| Others |
UniRef100:
UniRef100_Q3U2K5
UniRef90:
UniRef90_Q3U2K5
UniRef50:
UniRef50_Q6B0I6
UniGene:
Mm.240457
CCDS:
CCDS22822.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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