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24426 Gstp1

24426

Gstp1

glutathione S-transferase pi 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition glutathione S-transferase pi 1

研究结论

Date Results Publications
2018-04-07 10:38:00 The cytotoxic action of 2-acetylaminofluorene that give rise to the GST-P(+) single hepatocytes was suggested to be an injury to the excretory pump(s) and the duct of hepatocytes. A new physiological mechanism was hypothesized for the induction of preneoplastic cell populations in the rat liver instead of a genetic mechanism. 29501922
2016-03-19 10:49:00 Data suggest that expression of Gstp1 can be regulated by dietary factors; here, Gstp1 is induced in hepatocytes by carnosic acid, an anticarcinogenic component of rosemary (Rosmarinus officinalis). 25974399
2016-01-30 10:07:00 Data show that Valerian extract inhibits hepatocarcinogenesis by suppressing cell proliferation and inducing apoptosis in glutathione S-transferase pi GST-P(+) foci by activating gamma-aminobutyric acid A receptor GABA(A)RA1-mediated signaling. 25419570
2015-09-26 21:52:00 Cisplatin metabolism in different organs of rats correlated positively with specific GSTP1 activities and this enzyme may be a critical determinant of extent of cellular uptake or retention of cisplatin in renal and liver tissues. 24474500
2015-07-25 10:03:00 The influence of dietary lipids on the ontogeny of XMEs was also evaluated. mRNA and protein levels of phase I (CYP1A1, CYP1A2, and CYP1B1) and phase II (NAD(P)H:quinone acceptor oxidoreductase 1 and GSTP1) enzymes were analyzed. 25164943

名称对应

Type IDs
Synonymous GST-P, Gst3, Gstp, Gstp2
Gene
UniProtKB-ID: GSTP1_RAT, B6DYQ7_RAT
UniprotKB: P04906, B6DYQ7
UniParc: UPI000016794B
EMBL: BC058439, BC058440, L29427, CH473953, X02904, FJ179407
Ensembl: ENSRNOG00000018237
KO: rno:24426
Nucleutide sequences
EMBL-CDS: CAA26664.1, AAB59718.1, AAH58440.1, AAH58439.1, EDM12345.1, ACI32124.1
Gene_ORFName: rCG_48611
Ensembl_TRS: ENSRNOT00000024601
Protein sequencees
Ensembl_PRO: ENSRNOP00000024601
RefSeq: NP_036709.1
Others
UniRef100: UniRef100_P04906
UniRef90: UniRef90_P04906
UniRef50: UniRef50_P04906
UniGene: Rn.87063

全选

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