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24422 Gsta2

24422

Gsta2

glutathione S-transferase alpha 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition glutathione S-transferase alpha 2

研究结论

Date Results Publications
2012-08-11 11:00:00 The most sensitive, noninvasive biomarkers of HCBD-induced renal toxicity in Hanover Wistar rats were urinary alpha-GST and KIM-1. 21905055
2010-01-21 00:00:00 Single mutations are introduced to evaluate the importance of amino acids at the subunit interface of GSTA1-1. Phe52 and Arg69 are found to be major determinants of dimer formation: a single mutation at either position substantially hinders dimerization. 15035604
2010-01-21 00:00:00 a considerable amount of GSTs, in particular GSTA1-1, GSTA2-2, and GSTA3-3, corresponding to 10% of the cytosolic pool is electrostatically associated with the outer nuclear membrane, and a similar quantity is compartmentalized inside the nucleus 17197701
2010-01-21 00:00:00 Oltipraz-induced GSTA2 gene expression is dependent upon PI3-kinase-mediated nuclear translocation and binding of C/EBP-beta to the GSTA2 gene promoter. 12509401
2010-01-21 00:00:00 P.893: Ceramide inhibits C/EBP-beta or Nrf2 activation, which contributes to repression of GSTA2 gene transactivation. P. 897: "...ceramide inhibition of... transcription factors contributes to the repression of the GSTA2 gene transactivation." 15319326

名称对应

Type IDs
Synonymous Gsta1
Gene
UniProtKB-ID: GSTA1_RAT, B6DYP7_RAT
UniprotKB: P00502, B6DYP7
UniParc: UPI0000251101
EMBL: FJ179397, K01931, BC078706, CH473954
KO: rno:24422
Nucleutide sequences
EMBL-CDS: AAH78706.1, AAA41283.1, EDL77736.1, EDL77737.1, ACI32114.1
Gene_ORFName: rCG_26000
Protein sequencees
RefSeq: NP_058709.2, XP_017451587.1
Others
UniRef100: UniRef100_P00502
UniRef90: UniRef90_P00502
UniRef50: UniRef50_P00502
UniGene: Rn.144550

全选

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