| Type | Description |
|---|---|
| Definition | glutamate metabotropic receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-02 11:22:00 | Whereas both glutamate metabotropic receptor 2 and glutamate metabotropic receptor 4 couple to G proteins, G protein activation is mediated by mGlu4 heptahelical domain (HD) exclusively in glutamate metabotropic receptor 2-4 heterodimers. | 28829739 |
| 2018-05-19 11:37:00 | Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells remains elusive. Study identified mGlu2-4 specific pharmacological fingerprints that were also observed in a neuronal cell line and in lateral perforant path terminals naturally expressing mGlu2 and mGlu4. Results show the existence of mGlu2-4 heterodimers in native cells. | 28661401 |
| 2018-04-21 10:54:00 | This study investigated the role of mGluR4 in modulating two distinct forms of waiting impulsivity and its putative interaction with D2 receptors in modulating motor impulsivity on the five-choice serial reaction time task. The main findings indicate a prominent role of mGluR4 in modulating motor, and to some extent choice, impulsivity as well as aspects of visual attention. | 28487067 |
| 2016-08-27 10:19:00 | activation of mGluR4 prevents oxidative stress-induced NSC death and apoptotic-associated protein activities with involvement of inhibiting the JNK and p38 pathways in cell culture. | 26176363 |
| 2013-07-06 12:30:00 | mGluR4 promotes the proliferation of rat neural progenitor cells and cyclin D1 expression through activation of ERK1/2 signaling pathways in vitro. | 23374450 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GRM4_RAT
UniprotKB:
P31423
UniParc:
UPI000012F080
EMBL:
M92077,
M90518
KO:
rno:24417
|
| Nucleutide sequences |
EMBL-CDS:
AAA93190.1
|
| Protein sequencees |
RefSeq:
NP_073157.1
|
| Others |
UniRef100:
UniRef100_P31423
UniRef90:
UniRef90_P31423
UniRef50:
UniRef50_P31423
UniGene:
Rn.89046
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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