| Type | Description |
|---|---|
| Definition | glutamate metabotropic receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:05:00 | ERalphaDelta4, an ERalpha splice variant missing exon4, interacts with caveolin-3 and mGluR2/3. | 31050077 |
| 2020-03-21 11:19:00 | significant decrease in mGluR5 mRNA expression with a resultant increased expression of mGluR3 mRNA expression and hypermethylation of mGluR1 gene across both generations of rats, is reported. | 31710636 |
| 2019-02-23 10:44:00 | studies illustrate the significant contribution of mGluR2 to the antipsychotic-like, sleep and EEG effects of drugs acting on group II mGluRs; however, we also provide evidence of a role for mGluR3 activity in the control of sleep and wake cortical theta and gamma oscillations | 30005976 |
| 2018-04-21 10:11:00 | Results indicate a double function for glial mGlu3R activation against Abeta neurotoxicity: (i) it increases the release of protective neurotrophins such as sAPPalpha and BDNF, and (ii) it induces amyloid removal from extracellular space by glia-mediated phagocytosis. | 28495373 |
| 2018-01-06 11:49:00 | Findings suggest a time dependent evolving pattern of mGluR2/3 density during the pathogenesis of mesial temporal lobe epilepsy and provide insights for utilizing this data for in vivo imaging to predict the specific time points and responsiveness to the therapy targeting mGluR2/3. | 27565411 |
| Type | IDs |
|---|---|
| Synonymous | mGluR3 |
| Gene |
UniProtKB-ID:
GRM3_RAT
UniprotKB:
P31422
UniParc:
UPI000004E90A
EMBL:
M92076
Ensembl:
ENSRNOG00000005519
KO:
rno:24416
|
| Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000007572
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000007572
RefSeq:
XP_017447929.1,
XP_008760904.1,
NP_001099182.1
|
| Others |
UniRef100:
UniRef100_P31422
UniRef90:
UniRef90_P31422
UniRef50:
UniRef50_P31422
UniGene:
Rn.41715
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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