| Type | Description |
|---|---|
| Definition | glutamate metabotropic receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:05:00 | ERalphaDelta4, an ERalpha splice variant missing exon4, interacts with caveolin-3 and mGluR2/3. | 31050077 |
| 2019-03-30 13:08:00 | Compared to wild-type controls, mGluR2-knockout rats exhibited higher nucleus accumbens dopamine and locomotor responses to heroin and higher heroin self-administration. | 30283001 |
| 2019-02-23 10:44:00 | studies illustrate the significant contribution of mGluR2 to the antipsychotic-like, sleep and EEG effects of drugs acting on group II mGluRs; however, we also provide evidence of a role for mGluR3 activity in the control of sleep and wake cortical theta and gamma oscillations | 30005976 |
| 2018-06-02 11:22:00 | Whereas both glutamate metabotropic receptor 2 and glutamate metabotropic receptor 4 couple to G proteins, G protein activation is mediated by mGlu4 heptahelical domain (HD) exclusively in glutamate metabotropic receptor 2-4 heterodimers. | 28829739 |
| 2018-05-19 11:37:00 | Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells remains elusive. Study identified mGlu2-4 specific pharmacological fingerprints that were also observed in a neuronal cell line and in lateral perforant path terminals naturally expressing mGlu2 and mGlu4. Results show the existence of mGlu2-4 heterodimers in native cells. | 28661401 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GRM2_RAT
UniprotKB:
P31421
UniParc:
UPI000012F07F
EMBL:
M92075
Ensembl:
ENSRNOG00000013171
KO:
rno:24415
|
| Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000017607
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000017607
RefSeq:
NP_001099181.1,
XP_017450945.1,
XP_017450946.1
|
| Others |
UniRef100:
UniRef100_P31421
UniRef90:
UniRef90_P31421
UniRef50:
UniRef50_Q14416
UniGene:
Rn.9681
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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