| Type | Description |
|---|---|
| Definition | glutamate receptor, metabotropic 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:57:00 | Arc silence aggravates traumatic neuronal injury via mGluR1-mediated ER stress and necroptosis. | 31919348 |
| 2021-01-09 13:26:00 | Neuroprotective effects of mGluR5 activation through the PI3K/Akt pathway and the molecular switch of AMPA receptors. | 31600563 |
| 2020-08-13 18:50:00 | mGlu1 tonically regulates levels of calcium-permeable AMPA receptors in cultured nucleus accumbens neurons through retinoic acid signaling and protein translation. | 30222904 |
| 2020-05-16 11:02:00 | The protein levels of mGluR1 in cortical neurons were significantly increased by lysophosphatidic acid at 12 and 24h after treatment. LPA treatment induced ER stress and apoptosis in cortical neurons, and its neurotoxicity was partially mediated by Ca(2+) release from the ER via the Homer1/mGluR1 pathway. | 31369778 |
| 2020-03-21 11:38:00 | Findings suggest a common role for increased GluA1 translation, but not decreased mGlu1 function, in the incubation of methamphetamine and cocaine craving. We speculate that increased GluA1 translation near synapses may drive formation and synaptic insertion of homomeric GluA1 receptors in the absence of detectable changes in GluA1 protein levels. | 31146278 |
| Type | IDs |
|---|---|
| Synonymous | Gprc1a |
| Gene |
UniProtKB-ID:
GRM1_RAT,
Q9WTJ1_RAT,
G3V7U1_RAT
UniprotKB:
P23385,
Q9WTJ1,
G3V7U1
UniParc:
UPI000019BE4F,
UPI000002ADF0,
UPI000012F07E,
UPI000002ADEF,
UPI00000E897D
EMBL:
AABR07000215,
AABR07000208,
CH473994,
AABR07000212,
AABR07000211,
Y18810,
AABR07000210,
X57569,
AABR07000216,
AABR07000209,
AABR07000214,
AABR07000217,
M61099,
S48085,
Y18811,
AABR07000213
Ensembl:
ENSRNOG00000014290
KO:
rno:24414
|
| Nucleutide sequences |
EMBL-CDS:
AAA19497.1,
CAA40799.1,
AAB24138.1,
CAB51055.1,
CAB51056.1,
EDL93711.1
Gene_ORFName:
rCG_57330
Ensembl_TRS:
ENSRNOT00000044325,
ENSRNOT00000019319
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000047790,
ENSRNOP00000019319
RefSeq:
NP_058707.2,
NP_001107802.1,
XP_017444266.1
|
| Others |
UniRef100:
UniRef100_G3V7U1,
UniRef100_P23385,
UniRef100_P23385-2
UniRef90:
UniRef90_P23385-2,
UniRef90_P23385
UniRef50:
UniRef50_P23385,
UniRef50_P23385-2
UniGene:
Rn.87787
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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