| Type | Description |
|---|---|
| Definition | glutamate ionotropic receptor NMDA type subunit 2D |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:47:00 | UBP791 ((2S*,3R*)-1-(7-(2-carboxyethyl)phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid) inhibits GluN2C/2D with 40-fold selectivity over GluN2A-containing receptors, and that a methionine and a lysine residue in the ligand binding pocket are the critical molecular elements for the subtype-specific binding. | 31969570 |
| 2019-11-23 12:24:00 | Study supports a role for GluN2D-NMDARs in L-DOPA-induced dyskinesia (LID), and they confirm that cell-type and subunit specific modifications of NMDARs underlie the pathophysiology of LID. | 30261285 |
| 2014-03-15 11:17:00 | Data indicate that tetrahydroisoquinolines showed subunit-selective potentiation of NMDA receptors containing the GluN2C or GluN2D subunits. | 23627311 |
| 2014-01-11 11:24:00 | Data from molecular modeling suggest that GluN2D-containing NMDA receptors can enter a conformation or mode that allows the pore to gate with high probability of burst of activity. | 23578394 |
| 2011-11-05 10:30:00 | NR2D expression falls significantly from postnatal day P2 to P3, then levels off until P12, and declines again until P21. | 20887777 |
| Type | IDs |
|---|---|
| Synonymous | GluN2D |
| Gene |
UniProtKB-ID:
NMDE4_RAT
UniprotKB:
Q62645
UniParc:
UPI000002AF4F,
UPI0000130270
EMBL:
L31612,
D13214,
D13213,
U08260,
L31611
Ensembl:
ENSRNOG00000021063
KO:
rno:24412
|
| Nucleutide sequences |
EMBL-CDS:
BAA02500.1,
AAC37647.1,
AAC37646.1,
AAA17833.1,
BAA02501.1
Ensembl_TRS:
ENSRNOT00000028615
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000028615
RefSeq:
NP_073634.2,
XP_008757539.1,
XP_008757538.1
|
| Others |
UniRef100:
UniRef100_Q62645
UniRef90:
UniRef90_Q62645
UniRef50:
UniRef50_Q62645
UniGene:
Rn.91209
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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