| Type | Description |
|---|---|
| Definition | glutamate ionotropic receptor NMDA type subunit 2C |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:47:00 | UBP791 ((2S*,3R*)-1-(7-(2-carboxyethyl)phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid) inhibits GluN2C/2D with 40-fold selectivity over GluN2A-containing receptors, and that a methionine and a lysine residue in the ligand binding pocket are the critical molecular elements for the subtype-specific binding. | 31969570 |
| 2018-05-19 10:39:00 | a neuroprotective role of GluN2C, suggesting a mechanism by which GluN2C is upregulated to promote neuronal survival following ischemia. | 27845401 |
| 2015-12-19 10:06:00 | these findings highlight the isoform-specific structural and functional differences within the 14-3-3 family of proteins, which determine GluN2C binding and its essential role in targeting the receptor to the cell surface | 26229101 |
| 2014-09-13 11:31:00 | These results support a critical role for GluN2C receptors in the amygdala in the consolidation of learned fear responses. | 24008353 |
| 2014-03-15 11:17:00 | Data indicate that tetrahydroisoquinolines showed subunit-selective potentiation of NMDA receptors containing the GluN2C or GluN2D subunits. | 23627311 |
| Type | IDs |
|---|---|
| Synonymous | GluN2C, NR2C |
| Gene |
UniProtKB-ID:
NMDE3_RAT,
A0A0G2JSH8_RAT
UniprotKB:
Q00961,
A0A0G2JSH8
UniParc:
UPI000013026E,
UPI0000167A43
EMBL:
M91563,
AC094435,
CH473948,
D13212
Ensembl:
ENSRNOG00000003280
KO:
rno:24411
|
| Nucleutide sequences |
EMBL-CDS:
BAA02499.1,
AAA41713.1,
EDM06568.1,
EDM06567.1
Gene_ORFName:
rCG_35426
Ensembl_TRS:
ENSRNOT00000004477
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000004477
RefSeq:
XP_017452480.1,
NP_036707.3,
XP_017452481.1,
XP_017452478.1,
XP_006247769.1,
XP_006247771.1,
XP_017452477.1,
XP_017452479.1,
XP_017452475.1,
XP_017452476.1
|
| Others |
UniRef100:
UniRef100_Q00961
UniRef90:
UniRef90_Q00961
UniRef50:
UniRef50_Q00961
UniGene:
Rn.9709
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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