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24408 Grin1

24408

Grin1

glutamate ionotropic receptor NMDA type subunit 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition glutamate ionotropic receptor NMDA type subunit 1

研究结论

Date Results Publications
2021-03-20 13:33:00 The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors. 33122756
2020-10-24 13:55:00 Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors. 31444392
2020-10-03 12:58:00 Inhibition of MicroRNA 219 Expression Protects Synaptic Plasticity via Activating NMDAR1, CaMKIIgamma, and p-CREB after Microwave Radiation. 32553080
2020-07-11 11:44:00 Glutamate binding to the GluN2 subunit destabilizes the GluN1 glycine-binding cleft with larger conformational fluctuations. 32015122
2019-12-21 11:22:00 In aged rats, overall decreases in NR1, NR2A, and NR2B expression and reduction in neuronal and endothelial NOS activities in the rat cerebral cortex were found. The age-dependent changes in NR1 and NR2B correlated with neuronal NOS in both hemispheres. The effect of sleep deprivation was also studied. 31277281

名称对应

Type IDs
Synonymous GluN1, NMDAR1, NR1
Gene
UniProtKB-ID: NMDZ1_RAT, Q62648_RAT
UniprotKB: P35439, Q62648
UniParc: UPI000002AF53, UPI000002AF54, UPI000002AF55, UPI00000E5BDB, UPI000002AF58, UPI000002AF56, UPI000002AF57, UPI0000130283
EMBL: U08262, U08265, U08267, U08264, U08261, S39221, U08263, U08268, U08266, AY157515, S39218, X65227, S39220, X63255, AABR07051241, CH474001, S39219, S39217
Ensembl: ENSRNOG00000011726
KO: rno:24408
Nucleutide sequences
EMBL-CDS: AAB22435.1, AAB22431.1, AAB50932.1, CAA44914.1, AAB50929.1, CAA46335.1, AAB50928.1, AAB50927.1, AAB50930.1, AAB22432.1, AAA16366.1, AAB50926.1, AAB50933.1, AAB22434.1, AAB22433.1, AAB50931.1, EDL93607.1
Gene_ORFName: rCG_45539
Ensembl_TRS: ENSRNOT00000044246, ENSRNOT00000049297, ENSRNOT00000037725
Protein sequencees
Ensembl_PRO: ENSRNOP00000049198, ENSRNOP00000043301, ENSRNOP00000029227
RefSeq: NP_001274352.1, NP_001257537.1, NP_001257535.1, NP_001257534.1, NP_001257531.1, NP_001257532.1, XP_006233617.1, NP_058706.1, XP_006233618.1, NP_001257539.1
Others
UniRef100: UniRef100_P35439, UniRef100_Q62648
UniRef90: UniRef90_P35439, UniRef90_P35439-2
UniRef50: UniRef50_P35439, UniRef50_P35439-2
UniGene: Rn.9840

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