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24407 Grik5

24407

Grik5

glutamate ionotropic receptor kainate type subunit 5

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition glutamate ionotropic receptor kainate type subunit 5

研究结论

Date Results Publications
2014-07-12 12:26:00 These findings indicate that ligand binding to only the GluK5 subunit is both necessary and sufficient to allow trafficking of recombinant GluK2/K5 heteromers to the cell membrane, but that occupancy of the GluK2 site alone is not. 23975096
2013-06-22 11:31:00 GluK2 and GluK5 assemble with 2:2 stoichiometry. 22509486
2013-04-20 14:02:00 CaMKII-dependent phosphorylation of GluK5 is responsible for synaptic depression by untrapping of KARs from the PSD and increased diffusion away from synaptic sites. 23288040
2012-01-21 11:00:00 Heteromeric GluK2/K5 receptors expressed in human HEK-293T cells show markedly higher glutamate sensitivity than GluK2 homomers and do not desensitize at low glutamate concentrations. 22114280
2010-01-21 00:00:00 kainic acid-preferring glutamate receptors are responsive to changes in plasma glucose concentrations and may participate in the activation of the paraventricular neurones during hypoglycaemic stress 15796762

名称对应

Type IDs
Synonymous GluK5, iGlu5
Gene
UniProtKB-ID: GRIK5_RAT
UniprotKB: Q63273
UniParc: UPI000012B622
EMBL: Z11581, U08258
Ensembl: ENSRNOG00000020310
KO: rno:24407
Nucleutide sequences
EMBL-CDS: CAA77667.1, AAA17831.1
Ensembl_TRS: ENSRNOT00000027578
Protein sequencees
Ensembl_PRO: ENSRNOP00000027578
RefSeq: XP_006228444.1, NP_113696.1, XP_008757111.1
Others
UniRef100: UniRef100_Q61626
UniRef90: UniRef90_Q61626
UniRef50: UniRef50_Q61626
UniGene: Rn.74042

全选

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研究热度

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