| Type | Description |
|---|---|
| Definition | MAS-related GPR, member B2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:31:00 | Imiquimod-related dermatitis is mainly mediated by mast cell degranulation via Mas-related G-protein coupled receptor B2. | 32044660 |
| 2020-05-23 11:53:00 | granuloma formation during intrathecal morphine infusion was associated with MrgprB2/X2. Reducing MRGPRX2 potentially blocks morphine-induced side effects, including granuloma formation. | 31484729 |
| 2019-12-14 10:50:00 | Study investigated whether thimerosal induces pseudo-allergic reactions directly through MrgprB2 and MRGPRX2 on mast cells in vitro and in vivo and revealed that MrgprB2 mediates thimerosal-induced mast cell degranulation and pseudo-allergic reaction in mice. MRGPRX2 may be a key contributor to human contact dermatitis. | 31558225 |
| 2019-08-31 12:37:00 | The mast cell receptor Mrgprb2 is required for neurogenic inflammatory pain. | 30686732 |
| 2015-04-11 11:44:00 | basic secretagogues activate mouse mast cells in vitro and in vivo through a single receptor, Mrgprb2, the orthologue of the human G-protein-coupled receptor MRGPRX2 | 25517090 |
| Type | IDs |
|---|---|
| Synonymous | 4833406I20Rik, Mgrg14 |
| Gene |
UniProtKB-ID:
MRGB2_MOUSE,
W8W3G3_MOUSE
UniprotKB:
Q3KNA1,
W8W3G3
UniParc:
UPI00000234E4
EMBL:
AK029369,
AY042200,
BC107390,
HG426113,
BC107391
Ensembl:
ENSMUSG00000050425
KO:
mmu:243979
|
| Nucleutide sequences |
EMBL-CDS:
BAC26422.1,
AAI07391.1,
AAI07392.1,
AAK91796.1,
CDG86231.1
Ensembl_TRS:
ENSMUST00000052730
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000061878
RefSeq:
NP_780740.2
|
| Others |
UniRef100:
UniRef100_Q3KNA1
UniRef90:
UniRef90_Q3KNA1
UniRef50:
UniRef50_Q3KNA1
UniGene:
Mm.83689
CCDS:
CCDS21303.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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