| Type | Description |
|---|---|
| Definition | sialic acid binding Ig-like lectin G |
| Date | Results | Publications |
|---|---|---|
| 2017-06-03 12:20:00 | this study shows that Siglec-G inhibits dendritic cells cross-presentation by impairing such complex formation, and our results add insight into the regulation of cross-presentation in adaptive immunity | 27548433 |
| 2016-12-17 10:04:00 | The effect for Siglec-G deficiency in B cells results in higher B-1 cell numbers and a robust and preferential increase in oxidation-specific epitopes-specific IgM antibodies, which neutralize oxidized LDL-induced inflammation in vivo. | 26947073 |
| 2015-09-05 11:26:00 | Aging Siglec-G-deficient and Siglec-G 3/FcgammaRIIb double-deficient mice develop an autoimmune phenotype with elevated autoantibody levels and mild glomerulonephritis. | 25987743 |
| 2015-04-18 11:52:00 | Deficiency of SIGLEC-G was found to increase susceptibility to develop B-cell lymphoproliferative disorders. | 24859880 |
| 2015-03-07 11:01:00 | Siglec-G is recruited to the immunological synapse by sialic acid ligands on the Ag-bearing cells, producing a tolerogenic signal involving Lyn and the proapoptotic factor BIM that promotes deletion of the B cell and failure of mice to develop Abs to the Ag upon subsequent challenge. | 25252961 |
| Type | IDs |
|---|---|
| Synonymous | 9830164H23, A630096C01Rik, Siglec-G, Siglec10, mSiglec-G |
| Gene |
UniProtKB-ID:
SIG10_MOUSE,
Q8BY18_MOUSE
UniprotKB:
Q80ZE3,
Q8BY18
UniParc:
UPI00005AB685,
UPI0000006809
EMBL:
AY210400,
AC149091,
AK042488
Ensembl:
ENSMUSG00000030468
KO:
mmu:243958
|
| Nucleutide sequences |
EMBL-CDS:
AAO48273.1,
BAC31272.2
Ensembl_TRS:
ENSMUST00000005592
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005592
RefSeq:
NP_766488.2,
XP_006540923.1,
NP_001369415.1,
XP_036009001.1
|
| Others |
UniRef100:
UniRef100_Q80ZE3
UniRef90:
UniRef90_Q80ZE3
UniRef50:
UniRef50_Q80ZE3
UniGene:
Mm.24444
CCDS:
CCDS52221.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员