Type | Description |
---|---|
Definition | glucokinase |
Date | Results | Publications |
---|---|---|
2020-07-25 11:26:00 | Study in different rat models demonstrated that glucokinase (GCK)-mediated glucose phosphorylation is the rate-controlling step in insulin-stimulated hepatic glycogen synthesis in vivo under both normal and pathophysiological conditions of fatty liver-associated hepatic insulin resistance and it is controlled chiefly through GCK translocation. | 32188779 |
2016-04-16 11:11:00 | The enhancing effect of INGAP-PP on glucose-induced insulin release could be partly ascribed to its effect on glucokinase activity and glucose metabolism and is mainly mediated by the PI3K/AKT pathway. | 25906449 |
2015-04-25 10:25:00 | Arcuate nucleus glucokinase activation may represent a CNS mechanism that underlies the oft-described phenomena of the "sweet tooth" and carbohydrate craving. | 25485685 |
2014-12-20 10:06:00 | Atf3-silencing reversed ethanol-mediated Gck down-regulation and beta-cell dysfunction, followed by the amelioration of impaired glucose tolerance and insulin resistance. | 25074928 |
2014-11-22 10:57:00 | Chronic treatment with glucose kinase activators in animal models of diabetes provided sustained lowering of blood glucose. | 24772484 |
Type | IDs |
---|---|
Synonymous | GLK, GLUKA, RNGK2 |
Gene |
UniProtKB-ID:
HXK4_RAT,
X2G6B3_RAT,
Q64596_RAT
UniprotKB:
P17712,
X2G6B3,
Q64596
UniParc:
UPI000012CFAF,
UPI000002AB78,
UPI00000E8A93,
UPI000002AB79
EMBL:
CH473963,
M24948,
KJ026953,
J04218,
X53590,
M24943,
X53589,
M24944,
M58759,
M24949,
M24945,
X53588,
M24950,
M25806,
M30770,
AC110110,
M24952,
M24947,
M25807,
M24951
Ensembl:
ENSRNOG00000061527
KO:
rno:24385
|
Nucleutide sequences |
EMBL-CDS:
AAA41231.1,
AAA41230.1,
CAA37660.1,
AAA41229.1,
AAA41236.1,
AAA41239.1,
AAA41238.1,
CAA37657.1,
EDM00325.1,
AHN15398.1,
EDM00323.1,
CAA37658.1
Gene_ORFName:
rCG_35874,
rCG_35874
Ensembl_TRS:
ENSRNOT00000086474,
ENSRNOT00000086343,
ENSRNOT00000080147
|
Protein sequencees |
Ensembl_PRO:
ENSRNOP00000071435,
ENSRNOP00000069954,
ENSRNOP00000068656
RefSeq:
NP_001257778.1,
NP_001257779.1,
NP_036697.1,
XP_006251241.1
|
Others |
UniRef100:
UniRef100_Q64596,
UniRef100_P17712
UniRef90:
UniRef90_Q64596,
UniRef90_P35557
UniRef50:
UniRef50_Q64596,
UniRef50_P35557
UniGene:
Rn.10447
|
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