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243743 Plxna4

243743

Plxna4

plexin A4

protein-coding

Mus musculus

基因描述

Type Description
Definition plexin A4

研究结论

Date Results Publications
2020-11-28 13:13:00 Modular and Distinct Signaling Controls Dendrite Morphogenesis. 32499377
2020-04-18 11:19:00 The same anatomical and physiological consequences occur in Ednra(+/-); Plxna4(+/-) double heterozygotes, genetically confirming functional interaction. Second-order axon guidance therefore multiplexes a smaller number of guidance cues in sequential fashion, allowing precise refinement of axon trajectories. 30735130
2019-03-11 14:28:00 We show that PTP-3, a LAR homolog in Caenorhabditis elegans, participates in Sema2A-regulated axon guidance. PTPdelta, a member of vertebrate LAR class PTPs, is involved in Sema3A-regulated cortical dendritic growth. In Sema3A signaling, PTPdelta activates Fyn and Src kinases by dephosphorylating their C-terminal Tyr residues. 28637841
2018-03-31 12:18:00 These findings implicate Semaphorin-6A - Plexin-A2/Plexin-A4 interactions in dorsal lateral geniculate nucleus axon guidance and in the spatiotemporal organization of guidepost cell populations in the mammalian subpallium. 28438183
2017-08-05 12:10:00 These findings suggest that by interacting with PlexA4, TrkA plays a crucial role in redirecting local Sema3A signaling to retrograde axonal transport, thereby regulating dendritic GluA2 localization and patterning. 26945060

名称对应

Type IDs
Synonymous 9330117B14, Plxa4, mKIAA1550
Gene
UniProtKB-ID: PLXA4_MOUSE
UniprotKB: Q80UG2
UniParc: UPI0000603BBE
EMBL: AC158678, AK051614, AK220402, AC153867, AB073228, AC153629
Ensembl: ENSMUSG00000029765
KO: mmu:243743
Nucleutide sequences
EMBL-CDS: BAC56599.1, BAD90257.1, BAC34692.1
Ensembl_TRS: ENSMUST00000115096
Protein sequencees
Ensembl_PRO: ENSMUSP00000110748
RefSeq: NP_786926.2
Others
UniRef100: UniRef100_Q80UG2
UniRef90: UniRef90_Q80UG2
UniRef50: UniRef50_Q80UG2
UniGene: Mm.444029
CCDS: CCDS19985.2

全选

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