Type | Description |
---|---|
Definition | anoctamin 2 |
Date | Results | Publications |
---|---|---|
2020-07-04 11:03:00 | TMEM16b regulates action potential firing in lateral septum and aggression in male mice. | 31320449 |
2020-06-06 13:35:00 | Ano2/TMEM16B is a Ca2+-activated chloride channel in vagal afferents of nodose neurons and a major determinant of CCK-induced satiety, body weight control, and energy expenditure, making it a potential therapeutic target in obesity. | 30843875 |
2020-02-08 11:29:00 | Here the authors report that Ano2 knockout mice exhibit impaired anxiety-related behaviors and context-independent fear memory, thus implicating TMEM16B in anxiety modulation. | 31482844 |
2019-11-02 10:25:00 | Study provides the first in vivo evidence toward an alternative or additional role for Ano2 in the olfactory transduction cascade, where it may serve as a feedback mechanism to clamp olfactory receptor neurons spike output. | 30006552 |
2018-08-04 10:48:00 | Results of behavioral studies obtained from Ano2 (-/-) mice, a mouse line that was previously shown to lack this particular mode of ionic plasticity. The animals display motor coordination deficits that constitute a condition of mild ataxia. Moreover, motor learning is severely impaired in Ano2 (-/-) mice, suggesting cerebellar dysfunction. | 28536821 |
Type | IDs |
---|---|
Synonymous | BC033409, Tmem16b |
Gene |
UniProtKB-ID:
ANO2_MOUSE
UniprotKB:
Q8CFW1
UniParc:
UPI0001823FDA
EMBL:
BC033409,
FJ384096,
AK044763
Ensembl:
ENSMUSG00000038115
KO:
mmu:243634
|
Nucleutide sequences |
EMBL-CDS:
BAC32073.1,
ACL36051.1,
AAH33409.1
Ensembl_TRS:
ENSMUST00000160496
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125303
RefSeq:
NP_001351491.1,
XP_006506180.1,
XP_006506178.1,
NP_001351492.1,
XP_006506182.1,
NP_705817.2
|
Others |
UniRef100:
UniRef100_Q8CFW1
UniRef90:
UniRef90_Q8CFW1
UniRef50:
UniRef50_Q8CFW1
UniGene:
Mm.333398
CCDS:
CCDS39643.2
|
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Refseq |
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