| Type | Description |
|---|---|
| Definition | prickle planar cell polarity protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-30 10:03:00 | Exogenously introduced expression of green fluorescent protein (GFP)-tagged core PCP factors by electroporation revealed that Vangl1, Vangl2 and Prickle2 are localized on the ovarian side of the cell periphery in the oviduct.Our data collectively suggest that the mechanism for maintenance of Vangl2 asymmetry in mature mouse oviduct is different from the microtubule dependent polarized transport model | 27155041 |
| 2015-01-10 14:17:00 | The results of this study demonstrated that Prickle2 is required for normal ependymal motile cilia development and function. | 24708399 |
| 2014-05-31 11:18:00 | Prickle2 disruption causes behavioral abnormalities like altered social interaction, learning abnormalities and behavioral inflexibility. In mouse hippocampal neurons, it reduced dendrite branching, synapse number and postsynaptic density size. | 23711981 |
| 2012-05-05 11:16:00 | The cell polarity phenotype was efficiently rescued by nuclear but not cytoplasmic Prickle2, demonstrating the nuclear localization of Prickle2 is critical for its function. | 22333836 |
| 2012-04-28 11:21:00 | Prickle1 and Prickle2 promote neurite-like process formation of C1300 cells via the Dvl1-dependent mechanism | 22218901 |
| Type | IDs |
|---|---|
| Synonymous | 6230400G14Rik, 6720451F06Rik, mpk2 |
| Gene |
UniProtKB-ID:
PRIC2_MOUSE,
A7YQ68_MOUSE
UniprotKB:
Q80Y24,
A7YQ68
UniParc:
UPI00001C3921,
UPI0000512513
EMBL:
AC166101,
BC099897,
CH466523,
AC164636,
BC050793,
BC145754,
AC122429
Ensembl:
ENSMUSG00000030020
KO:
mmu:243548
|
| Nucleutide sequences |
EMBL-CDS:
AAI45755.1,
AAH50793.1,
EDK99322.1,
AAH99897.1
Ensembl_TRS:
ENSMUST00000113447,
ENSMUST00000113446,
ENSMUST00000113445,
ENSMUST00000032093
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109073,
ENSMUSP00000109072,
ENSMUSP00000109074,
ENSMUSP00000032093
RefSeq:
NP_001074615.1,
XP_030111245.1,
NP_001127932.1,
NP_001127933.1,
XP_036022012.1,
NP_001127931.1,
XP_006506169.1
|
| Others |
UniRef100:
UniRef100_Q80Y24,
UniRef100_A7YQ68
UniRef90:
UniRef90_Q80Y24
UniRef50:
UniRef50_Q80Y24
UniGene:
Mm.248820
CCDS:
CCDS51854.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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