| Type | Description |
|---|---|
| Definition | glutamate receptor interacting protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 15:43:00 | Results indicate that loss of Grip1/2 in cerebellar Purkinje cells contributes to increased repetitive self-grooming, a core autism behavior in mice | 31476380 |
| 2017-12-02 11:09:00 | Study performed social behavioral testing on neuron-specific Grip1/2-double knockout (DKO) and wild type (WT) mice and determined the expression profile of key signaling proteins in AMPAR, mGluR, mTOR, and GABA pathways in brain. Data Grip1/2-mediated AMPA signaling in regulating social behaviors and disturbance of glutamate- and GABA-signaling in specialized brain regions in autism-related social behavioral deficits. | 28063882 |
| 2014-09-13 10:41:00 | This study demonistrated that deletion of accumbal GRIP2 increases vulnerability to cue-induced cocaine relapse without altering the reinforcing properties of the drug or the response to natural rewards | 24126453 |
| 2013-02-16 11:29:00 | Identify Grip2 and Notch3 target regulating myogenic response of cerebral vessels. | 23117660 |
| 2010-12-04 10:27:00 | GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions. | 20956289 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
G3XA20_MOUSE
UniprotKB:
G3XA20
UniParc:
UPI0000024B30
EMBL:
AC162914,
AC118245
Ensembl:
ENSMUSG00000030098
KO:
mmu:243547
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000162300
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124709
RefSeq:
XP_006506167.1,
XP_006506165.2,
NP_001152979.1,
XP_011239653.1,
XP_006506166.1
|
| Others |
UniRef100:
UniRef100_G3XA20
UniRef90:
UniRef90_E0CXS4
UniRef50:
UniRef50_Q9C0E4-2
UniGene:
Mm.333264
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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