| Type | Description |
|---|---|
| Definition | leucine rich repeat transmembrane neuronal 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 13:56:00 | LRRTMs engage the protein domains of Nrx but require its heparan sulfate (HS) modification to induce presynaptic differentiation. Binding to HS of Nrx is sufficient for LRRTM3 and LRRTM4 to induce synaptogenesis. Nrx1gamma is a potent synapse organizer and LRRTM4 is its postsynaptic ligand. Mice expressing a mutant form of LRRTM4 that can't bind HS show structural and functional deficits at dentate gyrus excitatory syn... | 31995730 |
| 2020-07-18 11:31:00 | LRRTM4 is a key synapse organizing molecule at rod bipolar cell (RBC) terminals, where it regulates function of GABAergic synapse and assembly of RBC synaptic dyads. | 31974009 |
| 2013-11-16 11:20:00 | This study demonistrated that LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells. | 23911104 |
| Type | IDs |
|---|---|
| Synonymous | 7530419J18Rik, A230052N11 |
| Gene |
UniProtKB-ID:
LRRT4_MOUSE,
E9Q8Y9_MOUSE,
A0A0R4J1T4_MOUSE,
Q8BYQ8_MOUSE
UniprotKB:
Q80XG9,
E9Q8Y9,
A0A0R4J1T4,
Q8BYQ8
UniParc:
UPI00001F399D,
UPI0000217FCC,
UPI000002969D,
UPI00000EA4F9,
UPI0000183C52
EMBL:
AC153996,
AC113206,
AK032470,
AC153993,
AC156282,
AC157023,
AC153827,
BC037216,
AC153839,
AK038656,
AY182031
Ensembl:
ENSMUSG00000052581
KO:
mmu:243499
|
| Nucleutide sequences |
EMBL-CDS:
AAH37216.1,
BAC27887.1,
AAO67552.1,
BAC30084.1
Ensembl_TRS:
ENSMUST00000074662,
ENSMUST00000133918,
ENSMUST00000126005,
ENSMUST00000126399,
ENSMUST00000136421,
ENSMUST00000147663
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000074232,
ENSMUSP00000117445,
ENSMUSP00000115016,
ENSMUSP00000121124,
ENSMUSP00000121621,
ENSMUSP00000117263
RefSeq:
XP_006506151.1,
NP_001334190.1,
NP_001128215.1,
XP_006506149.1,
XP_006506150.1,
XP_006506148.1,
NP_001269031.1,
XP_011239638.1,
XP_036022004.1,
XP_006506152.1,
NP_848846.3
|
| Others |
UniRef100:
UniRef100_A0A0R4J1T4,
UniRef100_E9Q8Y9,
UniRef100_Q80XG9
UniRef90:
UniRef90_Q80XG9
UniRef50:
UniRef50_Q80XG9
UniGene:
Mm.483425
CCDS:
CCDS90065.1,
CCDS20259.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员