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243469 Igk

243469

Igk

immunoglobulin kappa chain complex

protein-coding

Mus musculus

基因描述

Type Description
Definition immunoglobulin kappa chain complex

研究结论

Date Results Publications
2021-03-06 13:30:00 Hepatocyte-Derived Igkappa Exerts a Protective Effect against ConA-Induced Acute Liver Injury. 33317072
2015-10-31 10:25:00 data suggest that Dnmt3a and Dnmt3b are critical to regulate the onset of Igkappa light chain rearrangement during early B-cell development 26059604
2013-04-13 10:29:00 ATM kinases activated by RAG DSBs during Igkappa recombination transduce transient H2AX/MDC1-independent signals that suppress initiation of further Igkappa rearrangements to control Igkappa allelic exclusion. 23382544
2012-12-22 11:14:00 using mouse immunoglobulin-kappa (Igkappa) as a model system, we demonstrate that although individual haematopoietic stem cells are characterized by allelic plasticity, early lymphoid lineage cells become committed to the choice of a single allele, and this decision is then stably maintained in a clonal manner that predetermines monoallelic rearrangement in B cells 23023124
2012-06-02 11:07:00 Igkappa rearrangements play an important role in receptor editing, a role that may explain why Igkappa recombination clearly fails to approach an equal rearrangement frequency for each variable (V) gene that might be considered optimal for diversity. 22287713

名称对应

Type IDs
Synonymous kappa
Gene
Nucleutide sequences
Protein sequencees
Others
UniGene: Mm.333124

全选

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