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24300 Cyp2b1

24300

Cyp2b1

cytochrome P450, family 2, subfamily b, polypeptide 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cytochrome P450, family 2, subfamily b, polypeptide 1

研究结论

Date Results Publications
2020-02-08 10:37:00 Study demonstrates that CYP2B1 is downregulated in a rat model of chronic kidney disease (CKD). CYP2B1 mRNA level was significantly decreased in CKD relative to control. 31049204
2018-06-02 12:09:00 Data suggest that liver oxidative damage induced by industrial fungicide bromuconazole is due, in part, to up-regulation of PXR/CYP3A1 expression and down-regulation of CAR/CYP2B1 expression. (PXR = pregnane X receptor; CYP3A1 = cytochrome P-450 3A1; CAR = constitutive androstane receptor; CYP2B1 = cytochrome P-450 2B1) 28532222
2017-02-18 12:18:00 Blast-induced traumatic brain injury was found to have a significant impact on CYP2B1 expression in liver. 26913515
2015-05-30 13:54:00 The induction of CYP2B by PB or CFA was comparable to nuclear CAR levels. CAR nuclear translocation was induced by CFA in both rat strains 25052003
2015-04-04 10:43:00 stimulation of hepatic heme oxygenase-1 expression by ascorbic acid deficiency caused the decrease in CYP content in liver 25036135

名称对应

Type IDs
Synonymous Cyp2b-1, Cypbe
Gene
UniProtKB-ID: A0A140UHW7_RAT, B2GV28_RAT
UniprotKB: A0A140UHW7, B2GV28
UniParc: UPI000019C292, UPI0000DA1C7B
EMBL: AABR07058025, CH473979, BC166502
Ensembl: ENSRNOG00000033680
KO: rno:24300, rno:108348266
Nucleutide sequences
EMBL-CDS: AAI66502.1, EDM07990.1
Gene_ORFName: rCG_53888
Ensembl_TRS: ENSRNOT00000044127, ENSRNOT00000091923, ENSRNOT00000079036
Protein sequencees
Ensembl_PRO: ENSRNOP00000049925, ENSRNOP00000074625, ENSRNOP00000075638
RefSeq: NP_001128316.1, XP_017450146.1, XP_008763713.1, XP_008763715.1, XP_008763714.1
Others
UniRef100: UniRef100_B2GV28, UniRef100_A0A140UHW7
UniRef90: UniRef90_P00176, UniRef90_P04167
UniRef50: UniRef50_P00176
UniGene: Rn.228579

全选

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