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24296 Cyp1a1

24296

Cyp1a1

cytochrome P450, family 1, subfamily a, polypeptide 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cytochrome P450, family 1, subfamily a, polypeptide 1

研究结论

Date Results Publications
2021-04-13 10:14:00 Aryl Hydrocarbon Receptor is Involved in the Proinflammatory Cytokine Response to Cadmium. 33766215
2020-10-03 12:57:00 Prediction of regioselectivity and preferred order of CYP1A1-mediated metabolism: Solving the interaction of human and rat CYP1A1 forms with ligands on the template system. 31974042
2018-10-06 11:49:00 Assessment of the pulmonary CYP1A1 metabolism of mavoglurant (AFQ056) in rat. 28879796
2018-07-21 12:16:00 CYP1A1 and CYP1B1 mRNA expression levels were significantly reduced from day 7 and 10, respectively. These results suggested that CpG island hypermethylation of the CYP1A1 and CYP1B1 promoters regulate the low expression of genes involved in the occurrence of isoniazidinduced liver injury 29115507
2018-02-10 10:17:00 We showed that the enhanced activity of the CYP1A1 mutant towards TCDD was due to more efficient binding of the substrate in the active site even though the mutated site was over 2.5nm away from the catalytic center 28780123

名称对应

Type IDs
Synonymous AHH, AHRR, CP11, CYP1, Cyp45c, Cypc45c, P-450MC, P1-450, P450-C, P450DX
Gene
UniProtKB-ID: CP1A1_RAT
UniprotKB: P00185
UniParc: UPI00001281A2
EMBL: M26129, X00469, K02246
Ensembl: ENSRNOG00000019500
KO: rno:24296
Nucleutide sequences
EMBL-CDS: CAA25153.1, AAA41025.1, AAA41027.1
Ensembl_TRS: ENSRNOT00000026473
Protein sequencees
Ensembl_PRO: ENSRNOP00000026473
RefSeq: NP_036672.3, XP_006243212.1
Others
UniRef100: UniRef100_P00185
UniRef90: UniRef90_P00185
UniRef50: UniRef50_P00185
UniGene: Rn.10352

全选

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